Products with Anti-diabetic bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN3828 | Troxerutin |
| Troxerutin protects against high cholesterol-induced cognitive deficits in mice, it could be recommended as a possible candidate for the prevention and therapy of cognitive deficits in type 2 diabetes mellitus and Alzheimer's disease. Troxerutin can attenuate renal injury induced by D-galactose probably through its antioxidant and anti-inflammation properties, it also has efficacy on streptozotocin-induced rat model in the early stage of diabetic retinopathy. | |
| BCN3858 | Kinsenoside |
| 1. Kinsenoside could be useful for repairing beta cells in pancreatic islet injury as well as improving its function, it could promote the glucose tolerance of acute glucose increase in both diabetic and normal healthy rats. 2. Kinsenoside shows significant antihepatotoxic activity. 3. Kinsenoside inhibits osteoclastogenesis from macrophages by attenuating RANKL-induced NF-κB and NFATc1 activities, which in turn, prevents bone loss from OVX mice. 4. Kinsenoside can inhibit the production of inflammatory mediators and enhanc anti-inflammatory cytokine generation, therefore, kinsenoside can alleviate acute inflammatory hazards. | |
| BCN3869 | Alliin |
| 1. Alliin protects against Lipopolysaccharides (LPS)-induced acute lung injury (ALI) by activating PPARγ, which subsequently inhibits LPS-induced NF-κB activation and inflammatory response, alliin may be used as an anti-inflammatory agent in the treatment of ALI. 2. Alliin has antiglycating potential , it offers protection against glucose or methyglyoxal induced glycation of superoxide dismutase. 3. Alliin has a good antiglycating effect and hence is expected to have therapeutic potential in the prevention of glycation-mediated diabetic complications. 4. Alliin and sabinene have detectable levels of antimicrobial activity. 5. Alliin has an inhibitory effect in osteoclasteogenesis with a dose-dependent manner via blocking the c-Fos-NFATc1 signaling pathway, it could be a potential therapeutic agent in the treatment of osteoporosis. | |
| BCN3930 | Palbinone |
| 1. Palbinone can induce HO-1 expression in the hepatic cells. 2. Palbinone shows a strong inhibitory activity on the reduced form of nicotinamide adenine dinucleotide phosphate (NADPH)-linked 3 alpha-hydroxysteroid dehydrogenase (3 alpha-HSD) of rat liver cytosol. | |
| BCN4102 | Tagitinin A |
| 1. Tagitinin A is a plant insecticidal compound. 2. Tagitinin A has phytotoxic activity, it shows significant inhibition of wheat coleoptile growth, seed germination, and the growth of STS and weeds. 3. Tagitinin A is a PPARα/γ dual agonist , it exerts anti-diabetic effect through PPARγ pathway. | |
