Products with Anti-diabetic bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN5291 | Ziyuglycoside II |
| Ziyuglycoside II has a wide range of clinical applications including hemostasis, antibiosis, anti-inflammation and anti-oxidation. Ziyuglycoside II has inhibitory effect on the growth of MDA-MB-435 cells, it induces cell cycle arrest and apoptosis through activation of ROS/JNK pathway in human breast cancer cells.Ziyuglycoside II methyl ester possess improved anti-diabetic properties, and has hepato-renal protective activities in type 2 diabetes. | |
| BCN5355 | Aucubin |
| Aucubin is an iridoid glycoside with a wide range of biological activities, including pancreas-protective, chondroprotective, antispasmodic, liver-protective, anti-inflammatory, anti-microbial, antioxidant, anti-algesic as well as anti-tumor activities. Aucubin prevents neuronal death in the hippocampal CA1 region in rats with diabetic encephalopathy, it also has protective effects on H2O2-induced apoptosis in PC12 cells. Aucubin may improve obesity-induced atherosclerosis by attenuating TNF-α-induced inflammatory responses. Aucubin suppresses hepatitis B viral DNA replication in vitro. | |
| BCN5392 | Rhaponiticin |
| Rhaponticin(Rhaponiticin) has a noticeable antidiabetic effect and could be potentially used as a new agent to treat type 2 diabetes mellitus and its complications, it can alleviate liver steatosis and improve blood glucose and lipid profiles in KK/Ay diabetic mice. | |
| BCN5492 | Gentianine |
| 1. Gentianine has anti-diabetic effect. 2. Gentianine has antipsychotic activity. 3. Gentianine has potential anti-inflammatory action, might be at least partly based on the suppressed production of TNF-alpha and IL-6. 4. Gentianine has diuretic activity, it could be developed as a safe antihypertensive drug. 5. Gentianine has hypotensive effect, it can produce a decrease in heart rate and systolic, diastolic and mean arterial blood pressure. 6. Gentianine has a protective effect on hippocampal CA1 neurons in rats subjected to recurrent febrile convulsion (FC), it can ameliorate FC-induced neuronal injury by enhancing glutamate acid decarboxylase activity, decreasing glutamate levels and increasing γ-aminobutyric acid levels. | |
| BCN5504 | Curcumin |
| Curcumin is a natural phenolic compound with diverse pharmacologic effects including antitumour, anti-bacteria, anti-fungicidal ,anti-edemic, hepatoprotective, anti-inflammatory, antioxidant, antiproliferative and antiangiogenic activities. Curcumin is an inhibitor of p300 histone acetylatransferase ((HATs)) and also shows inhibitory effects on NF-κB and MAPKs.Curcumin application causes markedly fast wound closure with well-formed granulation tissue dominated by fibroblast proliferation, collagen deposition, and complete early regenerated epithelial layer. | |
