Products with Anti-heroin dependence bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN4378 | Ibogaine |
| 1. Ibogaine has the propensity to prolong the QT interval of the electrocardiogram in humans, may generate life-threatening cardiac arrhythmias . 2. Ibogaine has promising anti-addictive property in animals. | |
| BCN5983 | Rotundine |
| Rotundine provides remarkable protection against cerebral ischemia reperfusion damage, its mechanisms may be through its influence on NO、ET 1 and energy metabolism. Rotundine injection can ameliorate the damages by modulating the activities of different types of NOS. It combined with methadone treatment may be a better therapeutic method in treatment of heroin dependence.Rotundine (L-tetrahydropalmatine, L-THP) is a selective antagonist of dopamine D1 receptor with IC50 of 166 nM. | |
