Products with Anti-inflammatory bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN6076 | Coronarin D |
| 1. Coronarin D inhibits NF-kappaB activation pathway, which leads to inhibition of inflammation, invasion, and osteoclastogenesis, as well as potentiation of apoptosis. 2. Coronarin D is active against tested Gram-positive bacteria, inactive for tested Gram-negative bacteria, and weakly active against tested fungi; using coronarin D-antibiotic drug combination can combat the infectious diseases . 3. Coronarin D shows promising antifungal activity against C. albicans in vitro, the minimum inhibitory concentration (MIC) and the minimum fungicidal concentration (MFC) were 2 and 4 mg/mL, respectively. | |
| BCN6105 | Vanillic acid |
| Vanillic acid is a flavoring agent which has hepatoprotective, free radical scavenging, antioxidant and anti-inflammatory properties. It exerts protective effects in isoproterenol induced cardiotoxic rats, has inhibitory effect on methylglyoxal-mediated glycation in apoptotic Neuro-2A cells via inhibition of glycation mechanisms including ROS, p38 and JNK, PKC and p47(phox). | |
| BCN6106 | Salvianolic acid B |
| Salvianolic acid B is a bioactive compound isolated from the Chinese medicinal herb Danshen, which is used for treating neoplastic and chronic inflammatory diseases in China, it shows a protective action against the ischemia-reperfusion induced injury in rat brain. It inhibited the expression of COX,ERK,TNF-α, NO. | |
| BCN6148 | Taraxerol |
| 1. Taraxerol has potent anti-inflammatory effects,it downregulates the expression of proinflammatory mediators in macrophages by interfering with the activation of TAK1 and Akt, thus preventing NF-κB activation. 2. Taraxerol can produce triterpenoid anti-cancer compound in Agrobacterium-transformed root cultures of butterfly pea (Clitoria ternatea L.). 3. Taraxerol can be used as a lipid biomarker for mangrove input to the SE Atlantic. 4. Taraxerol has inhibitory effects on AGS cell growth through inducing G2/M arrest and promotion of cell apoptosis, taraxeryl acetate has less effect on cell cycle arrest and apoptosis of AGS cells than taraxerol. | |
| BCN6154 | Hyptadienic acid |
| 1. Hyptadienic acid exhibits moderate cytotoxicity against HepG2 cells. 2. Hyptadienic acid shows a marked anti-inflammatory effect, it also exhibits strong antitumor-promoting activity in an in vivo two-stage carcinogenesis test of mouse tumor by using 7,12-dimethylbenz(a)anthracene (DMBA) as an initiator and TPA as a promoter. | |
