Products with Anti-inflammatory bioactivity

Cat.No. Product Name
BCN5942 Glycyrrhetinic acid
Glycyrrhetinic acid, an AChE activator, has anti-inflammatory,and antileukaemic activities. It is a potent inducer of mitochondrial permeability transition and can trigger the pro-apoptotic pathway, it has a low but definite affinity for mineralocorticoid receptors and thus appears to have a direct mineralocorticoid action.
BCN5945 Isoliquiritin
1. Isoliquiritoside has antioxidant activity,remarkable anti-tumor and anti-HIV effects. 2. Isoliquiritoside shows strong inhibition against pancreatic lipase ( IC50 of 37.6 uM ).
BCN5946 Liquiritigenin
Liquiritigenin, is an estrogenic compound which acts as an agonist selective for the β-subtype of the estrogen receptor, possesses anti-inflammatory, antihyperlipidemic, and antiallergic effects. Liquiritigenin can dose dependently alleviate mechanical, thermal and cold hyperalgesia, it may be potentially useful novel treatments for neuropathic pain. It exhibits antitumour action in pituitary adenoma cells via Ras/ERKs and ROS-dependent mitochondrial signalling pathways.
BCN5947 Rhein
Rhein has many pharmacological effects, including epatoprotective, nephroprotective, anti-inflammatory, antioxidant, anticancer, and antimicrobial activities, it has been proved effective in treatment of experimental diabetic nephropathy , one of the mechanism is the Inhibition of the hexosamine pathway. Rhein has protective effect on liver injury, the mechanisms possibly contribute to its action of antioxidant and anti-inflammatory activity, also associated with its effect of inhibiting TGF-β1 and suppressing the activation of hepatic stellate cells.
BCN5948 Ferulic acid
Ferulic acid is an antioxidant found naturally in plant cell walls , shows antioxidant activity in parallel with their radical scavenging activity, it has been approved in certain countries as food additive to prevent lipid peroxidation. Ferulic acid has been reported to have many physiological functions, including antioxidant, antimicrobial, anti-inflammatory, anti-thrombosis, anti- diabetic, and anti-cancer activities; it also protects against coronary disease, lowers cholesterol and increases sperm viability.Trans-Ferulic acid has antioxidant activity, it dose-dependently reduces lipid peroxidation induced by the three oxidants; it exerts a protective action on liver injury induced by chronic ethanol ingestion.

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