Products with Anti-inflammatory bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN5774 | Liriodendrin |
| 1. Liriodendrin has anti-inflammatory and antinociceptive activities. 2. Liriodendrin shows an excellent hypoglycemic activity. 3. Liriodendrin has protective effects on dopamine-induced cytotoxicity via its anti-oxidative properties by reducing ROS level and anti-apoptotic effect via protection of mitochondrion membrane potential (ΔΨm). 4. Liriodendrin may be a potent suppressor of CaCl(2)-induced arrhythmias, the prophylactic administration of liriodendrin is effective in prolonging latency of arrhythmia and reducing the occurrence of ventricular fibrillation from 75% to 25%. 5. Liriodendrin has inhibitory activities on gastritis and gastric ulcer, it can inhibit colonization of Helicobacter pylori effectively, it could be utilized for the treatment and/or protection of gastritis and gastric ulcer. 6. Liriodendrin plays protective role in sepsis-induced acute lung injury, it regulates lung inflammation, the phosphorylation of the NF-kB (p65) and expression of vascular endothelial growth factor (VEGF). | |
| BCN5778 | Stigmast-4-ene-3,6-dione |
| 1. Stigmast-4-ene-3,6-dione has anti-inflammatory and anti-allergic properties. | |
| BCN5779 | Carpachromene |
| 1. Carpachromene blocks protein expression of inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2) in LPS-stimulated macrophages, it could be a potential anti-inflammatory agent. 2. Carpachromene exhibits significant cytotoxicity against HepG2, PLC/PRF/5 and Raji cancer cell lines in vitro. 3. Carpachromene shows significant α-glucosidase inhibitory activity. | |
| BCN5790 | Aurantiamide |
| 1. Aurantiamide acetate may suppress the growth of malignant gliomas by blocking autophagic flux. 2. Aurantiamide acetate has an anti-neuroinflammatory effect on LPS stimulation through its inhibition of the NF-κB, JNK and p38 pathways. 3. Aurantiamide acetate inhibits cysteine proteinases, in particular, cathepsin L (3.4.22.15) and B (3.4.22.1) with IC50 of 12 microM and 49 microM, respectively . 4. Aurantiamide acetate is the main active substance of EECTD, which has significant anti-inflammatory and antinociceptive activities. | |
| BCN5791 | Suberosin |
| Suberosin exhibits anti-inflammatory, and anticoagulant activities, it also shows biting deterrent activity against Aedes aegypti, it may be useful for use as mosquito larvicidal agent. Suberosin inhibits PHA-induced PBMC proliferation, at least in part, through reduction of [Ca2+]i, ERK, NF-AT, and NF-kappaB activation, and early gene expression in PBMC including cyclins and cytokines, and arrest of cell cycle progression in the cells. | |
