Products with Anti-inflammatory bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN5759 | Hinokiol |
| 1. Hinokiol demonstrates potent activity against clinical isolates of methicillin-resistant Staphylococcus aureus (MRSA). 2. Hinokiol has significant inhibitory effects on 5-hydroxy-eicosa-tetra-enoic acid (5-HETE) and leukotriene B(4) (LTB4) formations, suggests that it has anti-inflammatory activity. | |
| BCN5763 | Tanshinone IIA |
| Tanshinone IIA is an estrogen receptor partial agonist with antiandrogenic properties, it has neuroprotective effects against cerebral ischemia/reperfusion injury and traumatic injury of the spinal cord in rats. Tanshinone IIA has anti-leukemia, anti-inflammatory and anti-oxidative properties, inhibits the release of inflammatory cytokines, such as, IL-1 β, IL-6 α, TNF-α. | |
| BCN5768 | Xanthohumol |
| Xanthohumol has anti-hepatitis C virus, anti-carcinogenic, free radical-scavenging, and anti-inflammatory activities, it can inhibit HIV-1 induced cytopathic effects, the production of viral p24 antigen and reverse transcriptase in C8166 lymphocytes at non-cytotoxic concentration. Xanthohumol may play a role in improving cognitive flexability in young animals. Xanthohumol has beneficial effects on markers of metabolic syndrome, it lowers body weight and fasting plasma glucose in obese male Zucker fa/fa rats.Valosin-containing protein (VCP) inhibitor. Binds to the N domain of VCP, impairing autophagosome function and maturation. Inhibits proliferation and induces apoptosis in a variety of human cancer cell lines. Also inhibits DGAT in rat liver microsomes (IC50 = 50.3 μM). | |
| BCN5771 | Avicularin |
| Avicularin exhibits anti-inflammatory activity through the suppression of ERK signaling pathway in LPS-stimulated RAW 264.7 macrophage cells; it inhibits the accumulation of the intracellular lipids by decreasing C/EBPα-activated GLUT4-mediated glucose uptake in adipocytes and potently inhibiting fatty acid synthase. | |
| BCN5772 | Engeletin |
| Engeletin, a bioactive flavonoid, has multiple biological activities such as anti-diabetic and anti-inflammatory effects. Engeletin possesses potent inhibition of PGE2 release with IC50 values of 19.6 μg/ml; it inhibits a recombinant human aldose reductase (IC50 value=1.16 microM). | |
