Products with Anti-inflammatory bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN3555 | Procurcumenol |
| 1. Procurcumenol is inhibitors of Nitric Oxide. 2. Procurcumenol and epicurcumenol have inhibitory effects on release of tumor necrosis factor-a (TNF-a). | |
| BCN3560 | Zedoarondiol |
| 1. Zedoarondiol has anti-inflammatory activity, inhibits iNOS, COX-2, and pro-inflammatory cytokine expressions by suppressing the phosphorylations of IKK and MAPKs, and by subsequently inactivating the NF-kappaB pathway. 2. Zedoarondiol dose-dependently inhibits LPS-stimulated nitric oxide (NO), prostaglandin E(2) (PGE(2)), tumor necrosis factor-alpha (TNF-alpha), interleukin-6 (IL-6), and interleukin-1beta (IL-1beta) productions in RAW 264.7 macrophage and in mouse peritoneal macrophage cells. | |
| BCN3565 | Yangonin |
| Yangonin is a novel CB₁ receptor ligand, it exhibits affinity for the human recombinant CB₁ receptor, it is also an effective inhibitor of EV-A71 infection in the low-micromolar. Yangonin could be a valuable candidate for the intervention of NF-κB-dependent pathological conditions such as inflammation.Yangonin induces autophagy and sensitizes bladder cancer cells to flavokawain A and docetaxel via inhibition of the mTOR pathway. | |
| BCN3568 | Flavokawain B |
| Flavokawain B, the hepatotoxic constituent from kava root, induces GSH-sensitive oxidative stress through modulation of IKK/NF-κB and MAPK signaling pathways. Flavokawain B has potent anti-inflammatory, and anti-cancer activities, it can significantly inhibit production of NO and PGE2 in LPS-induced RAW 264.7 cells. Flavokawain B acts through ROS generation and GADD153 up-regulation to regulate the expression of Bcl-2 family members, thereby inducing mitochondrial dysfunction and apoptosis in HCT116 cells. | |
| BCN3569 | 5,7-Dimethoxyflavanone |
| 1. 5,7-Dimethoxyflavanone has anti-inflammatory activities. | |
