Products with Anti-inflammatory bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN3858 | Kinsenoside |
| 1. Kinsenoside could be useful for repairing beta cells in pancreatic islet injury as well as improving its function, it could promote the glucose tolerance of acute glucose increase in both diabetic and normal healthy rats. 2. Kinsenoside shows significant antihepatotoxic activity. 3. Kinsenoside inhibits osteoclastogenesis from macrophages by attenuating RANKL-induced NF-κB and NFATc1 activities, which in turn, prevents bone loss from OVX mice. 4. Kinsenoside can inhibit the production of inflammatory mediators and enhanc anti-inflammatory cytokine generation, therefore, kinsenoside can alleviate acute inflammatory hazards. | |
| BCN3861 | Polygalacin D |
| 1. Polygalacin D can inhibit the expression of lipopolysaccharide (LPS)-induced iNOS and COX-2 protein and mRNA without an appreciable cytotoxic effect on RAW 264.7 macrophages, and can suppress induction by LPS of pro-inflammatory cytokines such as prostaglandin E2 (PGE2). 2. Polygalacin D2 exhibits significant inhibition on the proliferation of five kinds of cultured human tumor cell lines, i. e., A549 (non-small cell lung), SK-OV-3 (ovary), SK-MEL-2 (melanoma), XF498 (central nerve system) and HCT-15 (colon), in vitro. 3. Polygalacin D shows hepatoprotective activities against HSC-T6 cell line in vitro. | |
| BCN3869 | Alliin |
| 1. Alliin protects against Lipopolysaccharides (LPS)-induced acute lung injury (ALI) by activating PPARγ, which subsequently inhibits LPS-induced NF-κB activation and inflammatory response, alliin may be used as an anti-inflammatory agent in the treatment of ALI. 2. Alliin has antiglycating potential , it offers protection against glucose or methyglyoxal induced glycation of superoxide dismutase. 3. Alliin has a good antiglycating effect and hence is expected to have therapeutic potential in the prevention of glycation-mediated diabetic complications. 4. Alliin and sabinene have detectable levels of antimicrobial activity. 5. Alliin has an inhibitory effect in osteoclasteogenesis with a dose-dependent manner via blocking the c-Fos-NFATc1 signaling pathway, it could be a potential therapeutic agent in the treatment of osteoporosis. | |
| BCN3877 | Alpha-caryophyllene |
| Alpha-humulene and trans-caryophyllene extracted from S.officinalis essential oil can inhibit tumor cell growth; they also show marked anti-inflammatory effects, probably by interfering with TNFalpha production. | |
| BCN3904 | Daturaolone |
| 1. Daturaolone has potency in reducing the harmful effects or in maintaining the normal hepatic physiological mechanisms in both acute and chronic hepato-toxic induced liver damage in rats. 2. Daturaolone possesses in vivo anti-inflammatory and antinociceptive potentials, which are supported in silico by an interaction with COXs receptors. | |
