Products with Anti-inflammatory bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN4043 | Pellitorine |
| 1. Pellitorine shows strong cytotoxic activities against HL60 and MCT-7 cell lines. 2. Pellitorine can suppress expression of inducible NO synthase and cyclooxygenase-2. 3. Pellitorine shows antiprotozoal activity against Plasmodium falciparum (IC50 = 3.3 ug/mL). 4. Pellitorine is a potential larvicide with a specific target site and a lead molecule for the control of mosquito populations. 5. Pellitorine shows potent antiplatelet aggregation activity. | |
| BCN4074 | Methyleugenol |
| Methyleugenol (ME) is a natural constituent of the essential oils of a number of plants widely used in foodstuffs as flavouring agents, in view of the carcinogenic potential of ME, the need to check its presence in food products with effective analytical methods. ME has elaxant and antispasmodic actions on guinea-pig isolated ileum, it also has antinociceptive, anti-inflammatory, and insecticidal properties.ME can inhibit the production of nitric oxide and decreased the protein expression of inducible nitric oxide synthase, it down-regulates the production of pro-inflammatory cytokines in the ischemic brain as well as in immunostimulated mixed glial cells. | |
| BCN4094 | Darutoside |
| Darutoside can improve skin elasticity, surface appearance and stretch mark removal, through soothing the skin, decreasing inflammation, restoring collagen and promoting collagen production; it could as an appropriate treatment for wounds. | |
| BCN4099 | beta-Amyrin palmitate |
| 1. Beta-Amyrin palmitate may release norepinephrine from newly synthesized pools, and thus, it may activate noradrenergic activity. 2. Beta-Amyrin palmitate, like mianserin and imipramine, reduces the duration of immobility of mice significantly in a dose-dependent manner (5, 10 and 20 mg kg-1); (1)Beta-Amyrin palmitate or mianserin elicits a dose-related reduction in locomotor activity of mice and antagonizes locomotor stimulation induced by methamphetamine, imipramine increases locomotor activity and potentiates methamphetamine-induced hyperactivity; (2)Beta-Amyrin palmitate shows no effect on reserpine-induced hypothermia, whilst mianserin (10 mg kg-1) and imipramine (10 and 20 mg kg-1) antagonizes the reserpine-induced effect; (3)Beta-amyrin palmitate has similar properties in some respects to mianserin and might possess a sedative action. | |
| BCN4118 | Braylin |
| 1. Braylin has anti-inflammatory, antinociceptive and immunomodulatory effects, which possibly act through the glucocorticoid receptor activation and by inhibition of the transcriptional activity of NF-κB. 2. Braylin is a phosphodiesterase-4 inhibitor, it could represent an ideal prototype of glucocorticoid receptor ligand, able to induce synergic immunomodulatory effects. | |
