Products with Anti-inflammatory bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN4214 | Ethyl caffeate |
| Ethyl caffeate is a potent chemopreventive compound against skin carcinogenesis caused by solar UV exposure, it strongly inhibits neoplastic transformation of JB6 Cl41 cells without toxicity. PI3K, ERK1/2, and p38 kinase activities were suppressed by direct binding with HOEC in vitro. Ethyl caffeate also has anti-inflammatory, hepatprotective activities. | |
| BCN4225 | Catalposide |
| 1. Catalposide possesses antioxidant, anti-apoptotic, anti-microbial, anti-tumoral, and anti-inflammatory properties. 2. Catalposide is a potent inducer of HO-1 and HO-1 induction is responsible for the catalposide-mediated cytoprotection against oxidative damage. 3. Catalposide is a natural agonistic ligand of peroxisome proliferator-activated receptor-α, is hypolipidemic by activation of PPARαvia a ligand-mediated mechanism that modulates the expression of in lipid metabolism genes in hepatocytes. 4. Catalposide can attenuate induction of intestinal epithelial proinflammatory gene expression and reduce the severity of trinitrobenzene sulfonic acid-induced colitis in mice, it may be an effective agent for the treatment of diseases characterized by mucosal inflammation. | |
| BCN4237 | Trifolirhizin |
| Trifolirhizin possesses potential anti-inflammatory and anti-cancer activities, it inhibits acetylcholine mediated airway smooth muscle (ASM) contraction or directly relaxes pre-contracted ASM independent of β 2 -adrenoceptors. Trifolirhizin may be a a candidate as skin-whitening agents, it exerts varying degrees of inhibition on tyrosinase-dependent melanin biosynthesis. | |
| BCN4254 | Moracin C |
| 1. Moracin C and D, new phytoalexins from diseased mulberry, are antifungal compounds. 2. Moracin C has potent antibacterial activity, it can inhibit FabI and fatty acid synthesis, it inhibit S. aureus FabI with IC(50) of 83.8 uM. 3. Moracin C has anti-inflammatory effect, it can effectively reduce lipopolysaccharide (LPS) stimulated up-regulation of mRNA and protein expression of iNOS, COX-2, and serval pro-inflammatory cytokines (IL-1β, IL-6 and TNF-α. 4. Moracin may be protective influence in tumor promotion, utilization of Moracin may open a new avenue in the treatment of tumerigenesis. | |
| BCN4266 | Voleneol |
| 1. 1β,6α-Dihydroxyeudesm-4(15)-ene (Voleneol,DE) can attenuate the lipopolysaccharide (LPS)-induced inflammation in BV2 microglial cells, it also can dose-dependently suppress the protein expression of inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2),suggest thats DE may be a good candidate to regulate LPS-induced inflammatory response. | |
