VoleneolCAS# 70389-88-7 |
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| Cas No. | 70389-88-7 | SDF | Download SDF |
| PubChem ID | 14137570 | Appearance | Powder |
| Formula | C15H26O2 | M.Wt | 238.4 |
| Type of Compound | Sesquiterpenoids | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | (1S,2S,4aR,5R,8aS)-4a-methyl-8-methylidene-2-propan-2-yl-1,2,3,4,5,6,7,8a-octahydronaphthalene-1,5-diol | ||
| SMILES | CC(C)C1CCC2(C(CCC(=C)C2C1O)O)C | ||
| Standard InChIKey | WKKJGHCXVKEJNU-QRTUWBSPSA-N | ||
| Standard InChI | InChI=1S/C15H26O2/c1-9(2)11-7-8-15(4)12(16)6-5-10(3)13(15)14(11)17/h9,11-14,16-17H,3,5-8H2,1-2,4H3/t11-,12+,13+,14-,15-/m0/s1 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
The herbs of Curcuma wenyujin
| Description | 1. 1β,6α-Dihydroxyeudesm-4(15)-ene (Voleneol,DE) can attenuate the lipopolysaccharide (LPS)-induced inflammation in BV2 microglial cells, it also can dose-dependently suppress the protein expression of inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2),suggest thats DE may be a good candidate to regulate LPS-induced inflammatory response. |
| Targets | NO | PGE | NOS | COX |
Voleneol Dilution Calculator
Voleneol Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 4.1946 mL | 20.9732 mL | 41.9463 mL | 83.8926 mL | 104.8658 mL |
| 5 mM | 0.8389 mL | 4.1946 mL | 8.3893 mL | 16.7785 mL | 20.9732 mL |
| 10 mM | 0.4195 mL | 2.0973 mL | 4.1946 mL | 8.3893 mL | 10.4866 mL |
| 50 mM | 0.0839 mL | 0.4195 mL | 0.8389 mL | 1.6779 mL | 2.0973 mL |
| 100 mM | 0.0419 mL | 0.2097 mL | 0.4195 mL | 0.8389 mL | 1.0487 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Chemical constituents from aerial part of Curcuma wenyujin.[Pubmed:18338597]
Zhongguo Zhong Yao Za Zhi. 2007 Dec;32(24):2604-6.
OBJECTIVE: To investigate the chemical constituents from aerial part of Curcuma wenyujin. METHOD: Compounds were isolated by repeated column chromatography on silica gel. Their structures were elucidated on the basis of spectral analysis and comparison with literature data. RESULT: Six compounds were isolated and identified as codonolactone (1), Voleneol (2), octacosanoic acid (3), beta-sitosterol (4), mangdesisterol (5), and daucosterol (6). CONCLUSION: Compounds 1, 2, and 5 were isolated from the plant for the first time.
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