Products with Anti-inflammatory bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN3736 | 3-Deoxysappanchalcone |
| 1. 3-Deoxysappanchalcone is an effective HO-1 inducer at the translational level. 2. 3-Deoxysappanchalcone has anti-inflammatory effects, is a valuable compound for modulating inflammatory conditions. 3. 3-Deoxysappanchalcone has anti-influenza virus activity, the mechanism involved anti-apoptosis and anti-inflammation activities in vitro. 4. 3-Deoxysappanchalcone has inhibitory activity on MMP-9 expression and production in TNF-α-treated cells, is mediated by the suppression of AP-1 and NF-κB activation. | |
| BCN3740 | Dehydrotumulosic acid |
| 1. Dehydrotumulosic acid shows anti-inflammatory activity. | |
| BCN3741 | Poricoic acid A(F) |
| 1. Poricoic acid A(F) shows anti-inflammatory activity. | |
| BCN3757 | Viniferin |
| 1. α-Viniferin has anti-oxidant and anticancer activities. 2. ɛ-Viniferin and vincristine can enhance the anti-tumor effects efficiently by inducing HepG2 cell apoptosis. 3. α-Viniferin strongly inhibits the activities of the two CYPs dose dependently. 4. α-Viniferin suppresses the expression of proinflammatory genes iNOS and COX-2 in the early stage of inflammation by inhibiting the Akt/PI3K-dependent NF-κB activation and inhibits the production of proinflammatory mediators NO and PGE2 in the late stage by stimulating Nrf2-mediated HO-1 signaling pathway in LPS-stimulated BV2 microglial cells. | |
| BCN3790 | Isokaempferide |
| 1. Isokaempferide shows anti-inflammatory effects, the anti-inflammatory effects can be explained, at least in part, by reducing neutrophil degranulation, myeloperoxidase activity, mediators as well as TNF-alpha secretion. 2. Isokaempferide is used as a bronchodilator, can induce relaxation of guinea-pig isolated trachea. 3. The hydroxyflavones (luteolin, apigenin and isokaempferide) exert comparable antiproliferative activities against malignant and normal cells. 4. Isokaempferide shows strong inhibitory effect on TNF-alpha-induced liver cell death with the IC50 value of 22.8 microM, suggests that it has hepatoprotective activity. | |
