Dehydrotumulosic acidCAS# 6754-16-1 |
- 3-Epidehydrotumulosic acid
Catalog No.:BCN3649
CAS No.:167775-54-4
Quality Control & MSDS
Number of papers citing our products
Chemical structure
3D structure
| Cas No. | 6754-16-1 | SDF | Download SDF |
| PubChem ID | 216251 | Appearance | White powder |
| Formula | C31H48O4 | M.Wt | 484.7 |
| Type of Compound | Triterpenoids | Storage | Desiccate at -20°C |
| Solubility | Soluble in chloroform | ||
| Chemical Name | (2R)-2-[(3S,10S,13R,14R,16R,17R)-3,16-dihydroxy-4,4,10,13,14-pentamethyl-2,3,5,6,12,15,16,17-octahydro-1H-cyclopenta[a]phenanthren-17-yl]-6-methyl-5-methylideneheptanoic acid | ||
| SMILES | CC(C)C(=C)CCC(C1C(CC2(C1(CC=C3C2=CCC4C3(CCC(C4(C)C)O)C)C)C)O)C(=O)O | ||
| Standard InChIKey | LADJWZMBZBVBSB-DWSVKRSBSA-N | ||
| Standard InChI | InChI=1S/C31H48O4/c1-18(2)19(3)9-10-20(27(34)35)26-23(32)17-31(8)22-11-12-24-28(4,5)25(33)14-15-29(24,6)21(22)13-16-30(26,31)7/h11,13,18,20,23-26,32-33H,3,9-10,12,14-17H2,1-2,4-8H3,(H,34,35)/t20-,23-,24?,25+,26+,29-,30-,31+/m1/s1 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
||
| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
||
| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
| Description | 1. Dehydrotumulosic acid shows anti-inflammatory activity. |
| Targets | Immunology & Inflammation related |
Dehydrotumulosic acid Dilution Calculator
Dehydrotumulosic acid Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 2.0631 mL | 10.3157 mL | 20.6313 mL | 41.2626 mL | 51.5783 mL |
| 5 mM | 0.4126 mL | 2.0631 mL | 4.1263 mL | 8.2525 mL | 10.3157 mL |
| 10 mM | 0.2063 mL | 1.0316 mL | 2.0631 mL | 4.1263 mL | 5.1578 mL |
| 50 mM | 0.0413 mL | 0.2063 mL | 0.4126 mL | 0.8253 mL | 1.0316 mL |
| 100 mM | 0.0206 mL | 0.1032 mL | 0.2063 mL | 0.4126 mL | 0.5158 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
Calcutta University
University of Minnesota
University of Maryland School of Medicine
University of Illinois at Chicago
The Ohio State University
University of Zurich
Harvard University
Colorado State University
Auburn University
Yale University
Worcester Polytechnic Institute
Washington State University
Stanford University
University of Leipzig
Universidade da Beira Interior
The Institute of Cancer Research
Heidelberg University
University of Amsterdam
University of Auckland
TsingHua University
The University of Michigan
Miami University
DRURY University
Jilin University
Fudan University
Wuhan University
Sun Yat-sen University
Universite de Paris
Deemed University
Auckland University
The University of Tokyo
Korea University
- Helenalin
Catalog No.:BCN8073
CAS No.:6754-13-8
- Alpha-caryophyllene
Catalog No.:BCN3877
CAS No.:6753-98-6
- Thapsigargin
Catalog No.:BCC6952
CAS No.:67526-95-8
- 4-Methoxy-5-(3-morpholinopropoxy)-2-nitrobenzonitrile
Catalog No.:BCC8710
CAS No.:675126-26-8
- Spathulenol
Catalog No.:BCN4227
CAS No.:6750-60-3
- Arnidiol
Catalog No.:BCN3810
CAS No.:6750-30-7
- Eupatolide
Catalog No.:BCN7345
CAS No.:6750-25-0
- Fuegin
Catalog No.:BCN5809
CAS No.:6750-10-3
- DIDS
Catalog No.:BCC7942
CAS No.:67483-13-0
- GBR 12935 dihydrochloride
Catalog No.:BCC5380
CAS No.:67469-81-2
- Vanoxerine dihydrochloride
Catalog No.:BCC5129
CAS No.:67469-78-7
- GBR 12783 dihydrochloride
Catalog No.:BCC6676
CAS No.:67469-75-4
- Polygodial
Catalog No.:BCC7597
CAS No.:6754-20-7
- 8'-Epicleomiscosin A
Catalog No.:BCC3917
CAS No.:
- Nutlin-3b
Catalog No.:BCC1156
CAS No.:675576-97-3
- Nutlin-3a chiral
Catalog No.:BCC1812
CAS No.:675576-98-4
- PG 01037 dihydrochloride
Catalog No.:BCC7801
CAS No.:675599-62-9
- Lariciresinol dimethyl ether
Catalog No.:BCN4228
CAS No.:67560-68-3
- Maoyecrystal E
Catalog No.:BCN3283
CAS No.:675603-39-1
- Baicalein 7-O-beta-D-ethylglucuronide
Catalog No.:BCN7981
CAS No.:675624-38-1
- Diosbulbin G
Catalog No.:BCN4229
CAS No.:67567-15-1
- Hydrangenol 8-O-glucoside
Catalog No.:BCN4230
CAS No.:67600-94-6
- 5,7,2'-Trihydroxyflavanone
Catalog No.:BCC9241
CAS No.:120980-68-9
- Clerodermic acid methyl ester
Catalog No.:BCN4231
CAS No.:67650-47-9
High-performance liquid chromatographic method for the determination and pharmacokinetic study of dehydrotumulosic acid in the plasma of rats having taken the traditional chinese medicinal preparation Ling-Gui-Zhu-Gan decoction.[Pubmed:12705979]
J Chromatogr B Analyt Technol Biomed Life Sci. 2003 May 25;788(2):387-91.
A high-performance liquid chromatographic method for the determination of Dehydrotumulosic acid in plasma of rats having been administrated orally with the traditional Chinese medicinal preparation Ling-Gui-Zhu-Gan decoction was developed. Plasma samples taken from rats were acidified with hydrochloric acid and extracted with ethyl acetate. Separation of the main effective constituent Dehydrotumulosic acid was accomplished on a C(18) stationary phase and a mobile phase of methanol-acetonitrile-2% glacial acetic acid (13:12:10, v/v), with a UV detector setting at 242 nm. After validation, the method was used for preliminary investigation of the pharmacokinetic profiles of Dehydrotumulosic acid administrated in Ling-Gui-Zhu-Gan decoction.
The isolation, identification and determination of dehydrotumulosic acid in Poria cocos.[Pubmed:12036119]
Anal Sci. 2002 May;18(5):529-31.
Poria cocos (Fuling), a popular Chinese medicinal (CM) herb of fungal origin, has been included in many combinations with other CM herbs for its traditionally claimed activities of inducing diuresis, excreting dampness, invigorating the spleen and tranquilizing the mind and its modern pharmacological use of modulating the immune system of the body. Dehydrotumulosic acid, one of the effective constituents of Fuling, was isolated from the chloroform-soluble material of ethanol extract of the fungus. After further purification by a high-performance liquid chromatographic method on a C18 column, the purified constituent was identified using modern analytical techniques, such as UV, 13C-NMR and EI-MS. A reversed-phase high-performance liquid chromatographic method has been developed for the determination of Dehydrotumulosic acid in Poria cocos. The determination can be accomplished in less than 50 min using methanol-acetonitrile-2% glacial acetic acid as the mobile phase at a flow rate of 1.0 mL/min, with a UV detector setting at 242 nm and testosterone propionate used as an internal standard. This assay for Dehydrotumulosic acid is simple, rapid and with good reproducibility.
