Hydrangenol 8-O-glucosideCAS# 67600-94-6 |
Quality Control & MSDS
3D structure
Package In Stock
Number of papers citing our products
| Cas No. | 67600-94-6 | SDF | Download SDF |
| PubChem ID | 13962962 | Appearance | Powder |
| Formula | C21H22O9 | M.Wt | 418.4 |
| Type of Compound | Flavonoids | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | 3-(4-hydroxyphenyl)-8-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3,4-dihydroisochromen-1-one | ||
| SMILES | C1C(OC(=O)C2=C1C=CC=C2OC3C(C(C(C(O3)CO)O)O)O)C4=CC=C(C=C4)O | ||
| Standard InChIKey | IKTPWMTZNXOEIV-VRKGAULQSA-N | ||
| Standard InChI | InChI=1S/C21H22O9/c22-9-15-17(24)18(25)19(26)21(30-15)29-13-3-1-2-11-8-14(28-20(27)16(11)13)10-4-6-12(23)7-5-10/h1-7,14-15,17-19,21-26H,8-9H2/t14?,15-,17-,18+,19-,21-/m1/s1 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
||
| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
||
| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
| Description | Hydrangenol 8-O-glucoside may have anti-inflammary activity. |
| Targets | NF-kB | TNF-α | IL Receptor |
| In vitro | Turkish Scorzonera Species Extracts Attenuate Cytokine Secretion via Inhibition of NF-κB Activation, Showing Anti-Inflammatory Effect in Vitro.[Pubmed: 26729082]Molecules. 2015 Dec 30;21(1):E43.Scorzonera species are used in different folk medicines to combat many diseases, including the illnesses connected with inflammation. Previous experiments showed anti-inflammatory activity of Scorzonera extracts in vivo. S. latifolia, S. cana var. jacquiniana, S. tomentosa, S. mollis ssp. szowitsii, S. eriophora, S. incisa, S. cinerea, and S. parviflora extracts were, therefore, evaluated for their inhibitory activities of TNF-α and IL-1β production, and NF-κB nuclear translocation in THP-1 macrophages.
|
Hydrangenol 8-O-glucoside Dilution Calculator
Hydrangenol 8-O-glucoside Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 2.3901 mL | 11.9503 mL | 23.9006 mL | 47.8011 mL | 59.7514 mL |
| 5 mM | 0.478 mL | 2.3901 mL | 4.7801 mL | 9.5602 mL | 11.9503 mL |
| 10 mM | 0.239 mL | 1.195 mL | 2.3901 mL | 4.7801 mL | 5.9751 mL |
| 50 mM | 0.0478 mL | 0.239 mL | 0.478 mL | 0.956 mL | 1.195 mL |
| 100 mM | 0.0239 mL | 0.1195 mL | 0.239 mL | 0.478 mL | 0.5975 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
Calcutta University
University of Minnesota
University of Maryland School of Medicine
University of Illinois at Chicago
The Ohio State University
University of Zurich
Harvard University
Colorado State University
Auburn University
Yale University
Worcester Polytechnic Institute
Washington State University
Stanford University
University of Leipzig
Universidade da Beira Interior
The Institute of Cancer Research
Heidelberg University
University of Amsterdam
University of Auckland
TsingHua University
The University of Michigan
Miami University
DRURY University
Jilin University
Fudan University
Wuhan University
Sun Yat-sen University
Universite de Paris
Deemed University
Auckland University
The University of Tokyo
Korea University
- Diosbulbin G
Catalog No.:BCN4229
CAS No.:67567-15-1
- Baicalein 7-O-beta-D-ethylglucuronide
Catalog No.:BCN7981
CAS No.:675624-38-1
- Maoyecrystal E
Catalog No.:BCN3283
CAS No.:675603-39-1
- Lariciresinol dimethyl ether
Catalog No.:BCN4228
CAS No.:67560-68-3
- PG 01037 dihydrochloride
Catalog No.:BCC7801
CAS No.:675599-62-9
- Nutlin-3a chiral
Catalog No.:BCC1812
CAS No.:675576-98-4
- Nutlin-3b
Catalog No.:BCC1156
CAS No.:675576-97-3
- 8'-Epicleomiscosin A
Catalog No.:BCC3917
CAS No.:
- Polygodial
Catalog No.:BCC7597
CAS No.:6754-20-7
- Dehydrotumulosic acid
Catalog No.:BCN3740
CAS No.:6754-16-1
- Helenalin
Catalog No.:BCN8073
CAS No.:6754-13-8
- Alpha-caryophyllene
Catalog No.:BCN3877
CAS No.:6753-98-6
- 5,7,2'-Trihydroxyflavanone
Catalog No.:BCC9241
CAS No.:120980-68-9
- Clerodermic acid methyl ester
Catalog No.:BCN4231
CAS No.:67650-47-9
- Methylenetanshinquinone
Catalog No.:BCN3156
CAS No.:67656-29-5
- 9-Hydroxycamptothecin
Catalog No.:BCC8276
CAS No.:67656-30-8
- 1-Azakenpaullone
Catalog No.:BCC5332
CAS No.:676596-65-9
- Syringylpropane
Catalog No.:BCN3540
CAS No.:6766-82-1
- De-O-methylacetovanillochromene
Catalog No.:BCN4232
CAS No.:67667-62-3
- 8alpha-(2-Methylacryloyloxy)hirsutinolide 13-O-acetate
Catalog No.:BCN7107
CAS No.:67667-71-4
- (±)-trans-ACPD
Catalog No.:BCC6567
CAS No.:67684-64-4
- Anhydroglycinol
Catalog No.:BCN4053
CAS No.:67685-22-7
- Apigenin 6-C-alpha-L-arabinopyranosyl-8-C-beta-D-xylopyranoside
Catalog No.:BCN7820
CAS No.:677021-30-6
- Rediocide C
Catalog No.:BCN4233
CAS No.:677277-98-4
Turkish Scorzonera Species Extracts Attenuate Cytokine Secretion via Inhibition of NF-kappaB Activation, Showing Anti-Inflammatory Effect in Vitro.[Pubmed:26729082]
Molecules. 2015 Dec 30;21(1):E43.
Scorzonera species are used in different folk medicines to combat many diseases, including the illnesses connected with inflammation. Previous experiments showed anti-inflammatory activity of Scorzonera extracts in vivo. S. latifolia, S. cana var. jacquiniana, S. tomentosa, S. mollis ssp. szowitsii, S. eriophora, S. incisa, S. cinerea, and S. parviflora extracts were, therefore, evaluated for their inhibitory activities of TNF-alpha and IL-1beta production, and NF-kappaB nuclear translocation in THP-1 macrophages. The HPLC analysis was carried out to elucidate and to compare the composition of these extracts. Major compounds of the tested extracts have been isolated using different chromatographic techniques and further tested for their inhibitory activities on TNF-alpha and IL-1beta production. Several extracts showed promising anti-inflammatory activity in these in vitro tests. Results of HPLC analysis revealed chlorogenic acid as a compound present in all tested extracts. Hyperoside, quercetin-3-O-beta-d-glucoside and rutin were also present in varying amount in some Scorzonera species analyzed. Furthermore, eight phenolics which were identified as quercetin-3-O-beta-d-glucoside (1), hyperoside (2), hydrangenol-8-O-glucoside (3), swertisin (4), 7-methylisoorientin (5), 4,5-O-dicaffeoyl-quinic acid (6), 3,5-di-O-caffeoyl-quinic acid (7), and chlorogenic acid (8) have been isolated as major phenolic compounds of the tested extracts and, together with eight terpenoids (9-16) previously obtained from different Scorzonera species, have been tested for the inhibition of TNF-alpha production, unfortunately with no activity comparable with standard.
