Products with Anti-osteoarthritis bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN4872 | Bavachin |
| Bavachin is a phytoestrogen that activates the estrogen receptors ERα and ERβ with EC50s of 320 and 680 nM, respectively. It is a cholesterol acyltransferase inhibitor, may have therapeutic potential for type 2 diabetes by activating insulin signaling pathways. Bavachin can stimulate the genetic expression of VEGF in PB,and directly help the fracture healing, and potentially protect cartilage from inflammation-mediated damage in joints of osteoarthritis patients through decreasing IL-1β-induced activation of IKK-IκBα-NF-κB signaling pathway. Bavachin has suppressive effects against pigmentation by melanin in the skin. | |
| BCN4905 | Arteannuin L |
| 1. Arteannuin can degrade the level of TNF-α in rats with ostarthritis,and effectively inhibit the inflammation. 2. Arteannuin has antimalarial activity. | |
| BCN4906 | Arteannuin M |
| 1. Arteannuin can degrade the level of TNF-α in rats with ostarthritis,and effectively inhibit the inflammation. 2. Arteannuin has antimalarial activity. | |
| BCN4907 | Arteannuin N |
| 1. Arteannuin can degrade the level of TNF-α in rats with ostarthritis,and effectively inhibit the inflammation. 2. Arteannuin has antimalarial activity. | |
| BCN5549 | Astragalin |
| Astragalin (kaempferol-3-O-glucoside) is a flavonoid with anti-inflammatory activity, it inhibits the TLR4-mediated NF-κB and mitogen-activated protein kinases signaling pathways. Astragalin ameliorates oxidative stress-associated epithelial eosinophilia and apoptosis through disturbing TLR4-PKCβ2-NADPH oxidase-responsive signaling; it also can be effective in allaying ROS-promoted bronchial fibrosis through inhibiting autophagosome formation in airways. | |
