Products with Antibacterial bioactivity

Cat.No. Product Name
BCN2910 6,7,4'-Trihydroxyisoflavone
1. 6,7,4'-Trihydroxyisoflavone has antioxidant activity. 2. 6,7,4'-Trihydroxyisoflavone, is a novel inhibitor of PKCα in suppressing solar UV-induced matrix metalloproteinase 1. 3. 6,7,4'-trihydroxyisoflavone, suppresses adipogenesis in 3T3-L1 preadipocytes via ATP-competitive inhibition of PI3K. 4. 6,7,4'-trihydroxyisoflavone inhibits HCT-116 human colon cancer cell proliferation by targeting CDK1 and CDK2.
BCN2926 Juncusol
1. Juncusol shows significant activity against MRSA strains. 2. Juncusol can induce caspase-3-mediated cytotoxicity in HT22 cells. 3. Juncusol shows anxiolytic and sedative activities, it shows anxiolytic activity at dosages of 10 mg/kg.
BCN2927 Dehydroeffusol
1. Dehydroeffusol inhibits gastric cancer cell growth and tumorigenicity by selectively inducing tumor-suppressive endoplasmic reticulum stress and a moderate apoptosis. 2. Dehydroeffusol effectively inhibits human gastric cancer cell-mediated vasculogenic mimicry with low toxicity, it is a potential drug candidate for anti-gastric cancer neovascularization and anti-gastric cancer therapy. 3. Dehydroeffusol may antagonize the spasmogenic activity of various agents, and therefore, could be a promising agent in the treatment of spasms. 4. Dehydroeffusol possesses anxiolytic and sedative properties and does not affect the general movement coordination of mice. 5. Dehydroeffusol displays enhanced antimicrobial activities in light, its antimicrobial activities (minimum inhibitory concentrations) against methicillin-resistant and -sensitive Staphylococcus aureus and Candida albicans are increased 16 fold by irradiation with ultraviolet A (UVA).
BCN2963 Hydroxytyrosol acetate
Hydroxytyrosol acetate has antibacterial, neuroprotective , antioxidant and anti-inflammatory effects, it can enhance the fluorescent intensity of DNA binding molecules and mediated supercoiled DNA relaxation. Hydroxytyrosol acetate can improve the oxidative events and return pro-inflammatory proteins expression to basal levels probably through JAK/STAT, MAPKs and NF-κB pathways. Hydroxytyrosol acetate and polyphenols hydroxytyrosol administered orally can inhibit platelet aggregation in rats and that a decrease in thromboxane synthesis along with an increase in nitric oxide production contributed to this effect.
BCN2978 Sodium houttuyfonate
1. Sodium houttuyfonate is anti-pseudomonas agents, inhibits virulence related motility of Pseudomonas aeruginosa. 2. Sodium houttuyfonate inhibits biofilm formation and alginate biosynthesis-associated gene expression in a clinical strain of Pseudomonas aeruginosa in vitro. 3. Sodium houttuyfonate has anti-inflammatory activity, inhibits inflammation by blocking the MAPKs/NF-κB signaling pathways in bovine endometrial epithelial cells.

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