Products with Anticancer bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN2494 | Oxypeucedanin |
| Oxypeucedanin is a kind of open-channel blocker of the hKv1.5 channel and it prolongs the APD, it is an excellent candidate as an antiarrhythmic drug for atrial fibrillation.Oxypeucedanin has novel anticancer effect, mediated via induction of G2-M cell cycle arrest and apoptosis in human prostate carcinoma DU145 cells. | |
| BCN2509 | 11-Oxo-mogroside V |
| 11-Oxo-mogroside V is a natural sweetener, exhibits strong antioxidant activity. It exhibits significant inhibitory effects on reactive oxygen species (O2-, H2O2 and *OH) with EC50 of 4.79, 16.52, and 146.17 μg/mL, respectively. 11-Oxo-mogroside V exhibits the remarkable inhibitory effect on two-stage carcinogenesis test of mouse skin tumor induced by 7,12-dimethylbenz[a]anthracene (DMBA) as an initiator and TPA as a promoter. | |
| BCN2512 | 12-O-Tiglylphorbol-13-isobutyrate |
| 1. 12-O-Tetradecanoylphorbol-13-acetate has cytotoxic against in vitro P-388 lymphocytic leukemia and KB nasopharyngeal carcinoma cell. | |
| BCN2519 | Cucurbitacin IIb |
| Cucurbitacin IIb is one of the major active compounds in Hemsleyadine tablets which have been used for clinical treatment of bacillary dysentery, enteritis and acute tonsilitis. Cucurbitacin IIb exhibits its anti-inflammatory activity through modulating multiple cellular behaviors and signaling pathways, leading to the suppression of the adaptive immune response. Cucurbitacin IIb also can induce apoptosis of concanavalin A-activated mouse lymphocytes. | |
| BCN2521 | Eupalinilide B |
| Eupalinilides B demonstrates potent cytotoxicity against P-388 and A-549 tumor cell lines. | |
