Products with Anticancer bioactivity

Cat.No. Product Name
BCN2643 Tannic acid
Tannic acid has potential in the prevention of obesity.Tannic acid modifies silver nanoparticles are good candidates for microbicides used in treatment of herpesvirus infections.Tannic acid is directly harmful to larvae in a dose- and time-dependent manner and modulates immune responses of sheep WBC stimulated by H. contortus antigen by inhibiting Th1 cytokines and increasing Th2 cytokine expression in vitro.
BCN2644 trans-Caryophyllene
trans-Caryophyllene, a PPAR-α agonist, which has neuroprotective effects in various neurological disorders, such as chemical induced seizure and brain damage. trans-Caryophyllene suppresses the hypoxia-induced neuroinflammatory response through inhibition of NF-κB activation in microglia.trans-Caryophyllene also reduces both acute and chronic pain in mice, which may be mediated through the opioid and endocannabinoid systems.
BCN2651 Berberrubine
Berberrubine possesses diverse pharmacological activities, including glucose-lowering, lipid-lowering, anti-inflammatory, and anti-tumor effects. Berberrubine dose-dependently inhibits IL-8 and MCP-1 protein levels in the media and mRNA expression of the cells stimulated with IL-1beta or TNF-alpha.
BCN2655 Periplocin
Periplocin has anti-cancer, and potent immunoregulatory effects, it induces apoptosis and inhibits growth of cancer cells by the beta-catenin/Tcf signaling pathway. Periplocin is used for treatment of rheumatoid arthritis, reinforcement of bones and tendons, palpitations or shortness of breath and lower extremity edema in traditional medicine.
BCN2661 Amarogentin
1. Amarogentin incorporated in liposomes or niosomes may have clinical application in the treatment of leishmaniasis. 2. Amarogentin plays cemopreventive/therapeutic role during liver carcinogenesis through modulation of cell cycle and apoptosis. 3. Amarogentin prevents platelet activation through the inhibition of PLC γ2-PKC cascade and MAPK pathway, it may offer therapeutic potential for preventing or treating thromboembolic disorders.

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