Products with Anticancer bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN2724 | Tetrahydrocurcumin |
| Tetrahydrocurcumin can inhibit tumor angiogenesis, treat human breast cancer,and be a promising candidate for the prevention of CIPN by chemotherapeutic agents.Tetrahydrocurcumin exhibits protective effects against cisplatin-induced oxidative renal damage in rats by inhibiting cyclooxygenase-2 and caspase-3 activation; it has a protective effect over arsenic induced toxicity in rat. | |
| BCN2729 | Primin |
| Primin has antimycobacterial, and strong antineoplastic actions. Primin has potent activity against Trypanosoma brucei rhodesiense (IC50 0.144 microM) and Leishmania donovani (IC50 0.711 microM), and low cytotoxicity (IC50 15.4 microM) on mammalian cells; it could serve as a lead compound for the rational design of more potent and less toxic antiprotozoal agents. | |
| BCN2737 | Taccalonolide A |
| Taccalonolide A is the first microtubule stabilizing agent to be discovered from a plant since identification of the mechanism of action of paclitaxel and it is the first natural product steroid identified to have these cellular effects. | |
| BCN2739 | Trachelogenin |
| 1. Trachelogenin has antiproliferative effect, the mechanism is related to affect the phosphorylation of key proteins such as β-Catenin, c-Myc and GSK3 in the β-Catenin signaling pathway in a concentration-dependent manner. | |
| BCN2747 | Naringenin 5-rhamnoside |
| Naringenin chalcone has antiallergic, anti-inflammatory ,and anti-asthmatic properties, it inhibits the production of proinflammatory cytokines in the interaction between adipocytes and macrophages, and improves adipocyte metabolic functions and exerts insulin-sensitizing effects by activating an adiponectin-related pathway. | |
