Products with Anticancer bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN2905 | Clerosterol |
| 1. Clerosterol as a precursor of cyasterone, isocyasterone and 29-norcyasterone in biosynthesis of phytoecdysteroids of Ajuga hairy roots. 2. Clerosterol exerts its cytotoxic effect in A2058 human melanoma cells by caspases-dependent apoptosis. | |
| BCN2910 | 6,7,4'-Trihydroxyisoflavone |
| 1. 6,7,4'-Trihydroxyisoflavone has antioxidant activity. 2. 6,7,4'-Trihydroxyisoflavone, is a novel inhibitor of PKCα in suppressing solar UV-induced matrix metalloproteinase 1. 3. 6,7,4'-trihydroxyisoflavone, suppresses adipogenesis in 3T3-L1 preadipocytes via ATP-competitive inhibition of PI3K. 4. 6,7,4'-trihydroxyisoflavone inhibits HCT-116 human colon cancer cell proliferation by targeting CDK1 and CDK2. | |
| BCN2927 | Dehydroeffusol |
| 1. Dehydroeffusol inhibits gastric cancer cell growth and tumorigenicity by selectively inducing tumor-suppressive endoplasmic reticulum stress and a moderate apoptosis. 2. Dehydroeffusol effectively inhibits human gastric cancer cell-mediated vasculogenic mimicry with low toxicity, it is a potential drug candidate for anti-gastric cancer neovascularization and anti-gastric cancer therapy. 3. Dehydroeffusol may antagonize the spasmogenic activity of various agents, and therefore, could be a promising agent in the treatment of spasms. 4. Dehydroeffusol possesses anxiolytic and sedative properties and does not affect the general movement coordination of mice. 5. Dehydroeffusol displays enhanced antimicrobial activities in light, its antimicrobial activities (minimum inhibitory concentrations) against methicillin-resistant and -sensitive Staphylococcus aureus and Candida albicans are increased 16 fold by irradiation with ultraviolet A (UVA). | |
| BCN2947 | 10-Deacetyl-7-xylosyl paclitaxel |
| 1. 10-Deacetyl-7-xylosyl paclitaxel has long been used in Chinese clinics to treat cancer, it may target mitochondrial permeability transition pore (mPTP). | |
| BCN2949 | Irinotecan hydrochloride |
| Irinotecan hydrochloride is a water soluble topoisomerase I inhibitor mainly used to treat colon cancer and rectal cancer. | |
