Products with Anticancer bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN2696 | Pogostone |
| Pogostone possesses potent anti-bacterial and anti-fungal activities, it also exhibits an immunosuppressive property by directly blocking T cell proliferation as well as altering inflammatory cytokine profile. Pogostone could exert a gastro-protective effect against gastric ulceration, and the underlying mechanism might be associated with the stimulation of PGE2, improvement of antioxidant and anti-inflammatory status, as well as preservation of NP-SH. | |
| BCN2698 | Oxypeucedanin hydrate |
| Oxypeucedanin hydrate is an antimutagenic agent, it has antioxidant activity, and exhibits carbohydrate metabolizing enzymes inhibitory effect. | |
| BCN2701 | alpha-Solanine |
| 1. Alpha-Solanine alters antioxidative enzyme activities and MDA and PCO concentrations and GST activity in fat body and midgut. 2. Alpha-Solanine has proliferation-inhibiting and apoptosis-promoting effect on multiple cancer cells, such as clone, liver, melanoma cancer cells. | |
| BCN2702 | Gossypol |
| Gossypol is an effective natural antimicrobial agent against a wide range of potential fungal pathogens of cotton.Gossypol shows a significant increase in accumulation of acidic vesicular organelle, is a promising drug that induces autophagic cell death in radioresistant malignant glioma.Gossypol binds to Bcl-xL protein and Bcl-2 protein with Kis of 0.5-0.6 μM and 0.2-0.3 mM, respectively. | |
| BCN2704 | Karounidiol |
| 1. Karounidiol exhibits cytotoxicity especially against a human renal cancer. 2. Karounidiol markedly suppresses the promoting effect of TPA (1 microgram/mouse) on skin tumor formation in mice following initiation with 7,12-dimethylbenz[a]anthracene (50 micrograms/mouse). | |
