Products with Anticancer bioactivity

Cat.No. Product Name
BCN2663 Demethylwedelolactone
Demethylwedelolactone has trypsin inhibitory effect, it exerts anti-invasive growth effect on breast cancer cells.
BCN2665 Acetylshikonin
Acetylshikonin has anti-cancer and anti-inflammatory activity, it is a novel general P450 inhibitor with IC50 values of 1.4-4.0 μM for all tested P450s. Acetylshikonin exhibits weak cytotoxicity against human umbilical vein endothelial cells (HUVECs) with IC50 of over 20 microM, exhibits the antiangiogenic and antitumorigenic effects by suppressing proliferation and angiogenic factors. Certain shikonin derivatives(such as Acetylshikonin) act as modulators of the Nur77-mediated apoptotic pathway.
BCN2669 Corydine
1. Corydine shows antimicrobial activity. 2. Corydine shows antineoplastic activity. 3. Corydine is the adrenolytic and weak cholinergic agent. 4. Corydine shows irritant and respiratory stimulant and CNS depressant activities . 5. Injected intravenously in rabbits corydine produced an initial fall in blood pressure followed by a return to normal or above normal.
BCN2673 (-)-Curine
1. (-)-Curine can inhibit viability of hepatocellular carcinoma cells in regardless of p53 status.
BCN2676 Cucurbitacin S
Cucurbitacins from Wilbrandia ebracteata have analgesic effects. Cucurbitacin S has anticancer and antiinflammatory activities.

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