Products with Anticancer bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN2871 | Ganoderic acid M |
| 1. Ganoderic acid Me and/or ganoderic acid T have obvious action for inhibiting human tumor cell growth or proliferation, at the same time its toxicity for normal cells is low. | |
| BCN2881 | Ginsenoside F4 |
| Ginsenoside F4 has inhibitory effect on human lymphocytoma JK cell by inducing its apoptosis, the mechanism is related to the mitochondrial dysfunction and the increase of Bax expression and decrease of Bcl-2 expression. Ginsenoside F4 also has strongly inhibit activation of p38 mitogen-activated protein kinase in signal transduction pathways. | |
| BCN2891 | Sophoflavescenol |
| 1. Sophoflavescenol is a mixed inhibitor of PDE5 with a K(i) value of 0.005 microM. 2. Sophoflavescenol has antioxidant, anti-inflammatory, and apoptotic effects , these effects might contribute to the antitumor activity without severe side effects. 3. Sophoflavescenol exerts notable anti-inflammatory activity by inhibiting nitric oxide generation and tert-butylhydroperoxide-induced ROS generation rather than inhibiting nuclear factor kappa B activation in RAW 264.7 cells. | |
| BCN2892 | (2S)-Isoxanthohumol |
| 1. Isoxanthohumol shows an antiviral activity towards herpes viruses (HSV1 and HSV2) and bovine viral diarrhea virus (BVDV). 2. Isoxanthohumol is a polyphenol with antioxidant, anti-inflammatory, and antiangiogenic properties, seems to regulate in vivo vascular proliferation and stabilization and the EC-VSMC-inflammatory crosstalk. | |
| BCN2894 | Bruceine D |
| 1. Bruceine D from Brucea javanica, may have the potential to be used as a natural viricide, or a lead compound for new viricides. 2. Bruceine D inhibits the growth of three pancreatic cancer cell lines, i.e., PANC-1, SW1990 and CAPAN-1; induces cytotoxicity in Capan-2 cells via the induction of cellular apoptosis involving the mitochondrial pathway. | |
