Products with Anticancer bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN2758 | Hirsutine |
| Hirsutine has anticancer, cardioprotective, anti‑hypertensive and anti-arrhythmic activities, it also has vasodilatation activity, the mechanism is related to blockade of Ca2+ influx through L-type Ca2+ channels and inhibition of intracellular Ca2+ release may have no relationship with K+ channels. Hirsutine reduces the production of various neurotoxic factors in activated microglial cells and possesses neuroprotective activity in a model of inflammation-induced neurotoxicity. | |
| BCN2773 | Tomatidine |
| Tomatidine shows antibiotic, and anti-inflammatory activities, it significantly suppresses the activity of ACAT and leads to reduction of atherogenesis. Tomatidine inhibits the invasion of A549 cells by reducing the expression of MMPs, also inhibits ERK and Akt signaling pathways and NF-κB activity, suggests a new therapeutic potential for Tomatidine in anti-metastatic therapy. | |
| BCN2774 | Thonningianin A |
| Thonningianin A represents a new potent glutathione S-transferase in vitro inhibitor. Thonningianin A has anti-cancer and antioxidant properties, involves radical scavenging, anti-superoxide formation and metal chelation. | |
| BCN2780 | Puerarin 6''-O-xyloside |
| Puerarin 6''-O-xyloside possesses significant anti-osteoporotic activity on ovariectomy mice, it has significant antitumour activities, the mechanisms are related to increased levels of caspase-3, caspase-7, caspase-9 and Bax, and reduced levels Bcl-2. | |
| BCN2795 | Esculentoside H |
| Phytolaccaceae has anti-tumor activity, the mechanism may be related to the capacity of Esculentoside H for TNF release. | |
