Products with Anticancer bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN3125 | Tanshindiol C |
| 1. Tanshindiol C exhibits most powerful cytotoxic effects against tested tumor cells. 2. Tanshinones plays significant roles in the inhibition and induction of several CYP450 isozymes. | |
| BCN3129 | Neochamaejasmine A |
| Neochamaejasmin A can inhibit cellular (3)H-thymidine incorporation (IC 50 12.5 microg/mL) and subsequent proliferation of human prostate cancer LNCaP cells, it blocks cell cycle progression at the G1 phase by activating the p21 protein and ultimately promoting the Fas-caspase 8-caspase 3 apoptotic machinery. | |
| BCN3148 | Delphinidin-3-sambubioside chloride |
| 1. Delphinidin-3-sambubioside chloride has antioxidant activity. 2. Delphinidin-3-sambubioside might induce apoptosis in HL-60 cells through a ROS-mediated mitochondrial dysfunction pathway. | |
| BCN3149 | Quercetin-3-O-glucuronide |
| Quercetin-3-O-glucuronide is a potent stilbene oxidase inhibitor, it has antioxidant, anti-atherogenic, and anti-inflammatory activities. Quercetin-3-O-glucuronide significantly improves Alzheimer's disease (AD)-type deficits in hippocampal formation basal synaptic transmission and long-term potentiation, possibly through mechanisms involving the activation of the c-Jun N-terminal kinases and the mitogen-activated protein kinase signaling pathways. Quercetin-3-O-glucuronide is equally effective in inhibiting ROS-associated inflammation and ameliorating insulin resistant endothelial dysfunction by beneficial regulation of IRS-1 function. | |
| BCN3155 | Ferruginol |
| 1. Ferruginol has anti-plasmodial, leishmanicidal, anti-ulcerogenic activities. 2. Ferruginol has cardioprotective, anti-oxidative and anti-inflammatory activities. 3. Ferruginol has anticancer activity, can induce apoptosis in non-small cell lung cancer (NSCLC) cells. 4. Ferruginol has antimicrobial and antifungal activities against wood-rot fungi (basidiomycetes), can cause cellular dysfunction and damage, lead to growth inhibition and autophagic cell death of fungi. | |
