Products with Anticancer bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN3231 | Ponicidin |
| 1. Ponicidin has immunoregulatory and anti-inflammatory functions . 2. Ponicidin has anti-viral function especially in the upper respiratory tract infection. 3. Ponicidin has anti-leukemia activity, by inducing apoptosis, downregulation of survivin as well as Bcl-2 expressions. 4. Ponicidin has anti-cancer activity against gastric carcinoma and lung cancer; can inhibit growth and induce apoptosis of gastric carcinoma cell line MKN28, via the signaling pathway regulated by Janus kinase 2 (JAK2) and signal transducers and activators of transcription 3 (STAT3). | |
| BCN3254 | (-)-Pinoresinol |
| 1. Pinoresinol (PIN)can ameliorate CCl4-induced acute liver injury, and this protection is likely due to anti-oxidative activity and down-regulation of inflammatory mediators through inhibition of NF-kappaB and AP-1. 2. (+)-Pinoresinol possesses fungicidal activities and therapeutic potential as an antifungal agent for the treatment of fungal infectious diseases in humans. 3. Pinoresinol is the precursor of other dietary lignans that are present in whole-grain cereals, legumes, fruits, and other vegetables, PIN can cause an upregulation of the CDK inhibitor p21(WAF1/Cip1) both at mRNA and protein levels, suggests that this could be a mechanism by which PIN reduces proliferation and induces differentiation on HL60 cells. | |
| BCN3257 | Ganoderic acid C6 |
| Ganoderic acid C6 has antinociceptive activity. | |
| BCN3265 | 1-Dehydro-6-gingerdione |
| 1. 1-Dehydro-6-gingerdione is 5-HT1A receptor partial agonists. 2. 1-Dehydro-6-gingerdione has antioxidant and anti-inflammatory activities. 3. 1-Dehydro-6-gingerdione significantly suppresses the expression of inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2) proteins in a concentration-dependent fashion. | |
| BCN3266 | 8-Shogaol |
| 1. 8-Shogaol can induce apoptosis in a time- and concentration-dependent manner by reactive oxygen species production and depletion of glutathione in HL-60 cells. | |
