Products with Anticancer bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN3267 | 10-Shogaol |
| 1. 10-Shogaol, as an antioxidant for human skin cell growth and a migration enhancer with potential to be a novel wound repair agent. 2. 8- and 10-Shogaol have similar metabolic profiles to [6]-shogaol and exhibit similar toxicity toward human colon cancer cells. | |
| BCN3289 | Moracin P |
| 1. Moracin P shows significant nitric oxide (NO) production inhibitory effects in RAW264.7 cells. 2. Moracin P exhibits potent in vitro inhibitory activity against hypoxia-inducible factor (HIF-1), which is a key mediator during adaptation of cancer cells to tumour hypoxia. 3. Moracin P might protect neuronal cell death against the oxidative stress induced by oxygen-glucose deprivation(OGD), can enhance cell viability in dose-dependent manner against OGD-induced cell death in neuroblastoma SH-SY5Y cells. | |
| BCN3291 | Moracin T |
| 1. Moracin treatment can inhibit the double 12-O-tetradecanoylphorbol 13-acetate (TPA) treatment-induced morphological changes reflecting inflammatory response, including leucocyte infiltration, hyperplasia and cell proliferation; moracin treatment furthermore can significantly suppress the elevation in 4-HNE level and elevate expression of c-fos, c-myc and cycloxygenase-2 (COX-2) in normal epidermis induced by double application of TPA; the moracin may be protective influence in tumor promotion, utilization of Moracin may open a new avenue in the treatment of tumerigenesis. | |
| BCN3292 | Moracin M |
| 1. Moracin M is a phytoalexin. 2. Moracin M inhibits PDE4D2, PDE4B2, PDE5A1, and PDE9A2 with the IC(50) values of 2.9, 4.5, >40, and >100 μM, respectively. | |
| BCN3306 | Pallidol |
| Pallidol is a potent and selective singlet oxygen quencher in aqueous systems, it may be used in singlet oxygen-mediated diseases as a pharmacological agent. | |
