Pallidol

CAS# 105037-88-5

Pallidol

Catalog No. BCN3306----Order now to get a substantial discount!

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Quality Control of Pallidol

Number of papers citing our products

Chemical structure

Pallidol

3D structure

Chemical Properties of Pallidol

Cas No. 105037-88-5 SDF Download SDF
PubChem ID 484757 Appearance Powder
Formula C28H22O6 M.Wt 454.5
Type of Compound Phenols Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name (4bR,5R,9bR,10R)-5,10-bis(4-hydroxyphenyl)-4b,5,9b,10-tetrahydroindeno[2,1-a]indene-1,3,6,8-tetrol
SMILES C1=CC(=CC=C1C2C3C(C(C4=C(C=C(C=C34)O)O)C5=CC=C(C=C5)O)C6=CC(=CC(=C26)O)O)O
Standard InChIKey YNVJOQCPHWKWSO-ZBVBGGFBSA-N
Standard InChI InChI=1S/C28H22O6/c29-15-5-1-13(2-6-15)23-25-19(9-17(31)11-21(25)33)28-24(14-3-7-16(30)8-4-14)26-20(27(23)28)10-18(32)12-22(26)34/h1-12,23-24,27-34H/t23-,24-,27+,28+/m1/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Pallidol

The herbs of Cissus pallida

Biological Activity of Pallidol

DescriptionPallidol is a potent and selective singlet oxygen quencher in aqueous systems, it may be used in singlet oxygen-mediated diseases as a pharmacological agent.
TargetsROS
In vitro

Pallidol, a resveratrol dimer from red wine, is a selective singlet oxygen quencher.[Pubmed: 19101516]

Biochem Biophys Res Commun. 2009 Feb 6;379(2):283-7.

Pallidol is a naturally occurring resveratrol dimer from red wine with antioxidant and antifungal activities.
METHODS AND RESULTS:
In this report, with the use of the EPR spin-trapping technique, the scavenging and quenching effects of Pallidol on reactive oxygen species (ROS) were investigated. The results demonstrated that Pallidol showed strong quenching effects on singlet oxygen at very low concentrations, but it was ineffective to scavenge hydroxyl radicals or superoxide anions. Further kinetic study revealed that the reaction of Pallidol with singlet oxygen had an extremely high rate constant (k(a)=1.71x10(10)).
CONCLUSIONS:
Therefore, Pallidol is a potent and selective singlet oxygen quencher in aqueous systems. It may be used in singlet oxygen-mediated diseases as a pharmacological agent, which may contribute to the health beneficial effects of red wine.

Pallidol Dilution Calculator

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Pallidol Molarity Calculator

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Preparing Stock Solutions of Pallidol

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.2002 mL 11.0011 mL 22.0022 mL 44.0044 mL 55.0055 mL
5 mM 0.44 mL 2.2002 mL 4.4004 mL 8.8009 mL 11.0011 mL
10 mM 0.22 mL 1.1001 mL 2.2002 mL 4.4004 mL 5.5006 mL
50 mM 0.044 mL 0.22 mL 0.44 mL 0.8801 mL 1.1001 mL
100 mM 0.022 mL 0.11 mL 0.22 mL 0.44 mL 0.5501 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Pallidol

Pallidol, a resveratrol dimer from red wine, is a selective singlet oxygen quencher.[Pubmed:19101516]

Biochem Biophys Res Commun. 2009 Feb 6;379(2):283-7.

Pallidol is a naturally occurring resveratrol dimer from red wine with antioxidant and antifungal activities. In this report, with the use of the EPR spin-trapping technique, the scavenging and quenching effects of Pallidol on reactive oxygen species (ROS) were investigated. The results demonstrated that Pallidol showed strong quenching effects on singlet oxygen at very low concentrations, but it was ineffective to scavenge hydroxyl radicals or superoxide anions. Further kinetic study revealed that the reaction of Pallidol with singlet oxygen had an extremely high rate constant (k(a)=1.71x10(10)). Therefore, Pallidol is a potent and selective singlet oxygen quencher in aqueous systems. It may be used in singlet oxygen-mediated diseases as a pharmacological agent, which may contribute to the health beneficial effects of red wine.

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