Products with Anticancer bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN3330 | Trametenolic acid |
| 1. Trametenolic acid is a cytotoxic agent. 2. Trametenolic acid and Betulin as a new candidate of potent tyrosinase inhibitors, can decrease tyrosinase activity and melanin content. 3. Trametenolic acid exhibits a mode of mixed inhibition with a K I of 0.9 μM, K IS of 0.5 μM, and an IC50 of 7.25 μM. | |
| BCN3331 | Inotodiol |
| 1. Inotodiol shows significant anti-tumor and anti-tumor promoting activities, including human cervical cancer. 2. Inotodiol inhibits cell proliferation through apoptosis induction by activating caspase-3. 3. Inotodiol can inhibit proliferation and induce the apoptosis of A549 cells, and its molecular mechanism may be associated with the up-regulating expression of p53 and bax proteins and down-regulating expression of Bcl-2 protein, which arrested A549 cells in S phase. | |
| BCN3340 | Butyrospermol |
| 1. Butyrospermol acetate exhibits inhibitory effect on skin tumor promotion in an in vivo two-stage carcinogenesis test using 7,12-dimethylbenz [a] anthracene (DMBA) as an initiator and TPA as a promoter, the exceptionally high levels of triterpenes in shea fat, indicates that shea nuts and shea fat (shea butter) constitute a significant source of anti-inflammatory and anti-tumor promoting compounds. | |
| BCN3342 | Cucurbitadienol |
| 1. Cucurbitadienol has significant anti-inflammatory, anti-tumor effect, is also CucurbitacinBE compounds biosynthesis the key intermediate. 2. Cucurbitadienol synthase, the first committed enzyme for cucurbitacin biosynthesis, is a distinct enzyme from cycloartenol synthase for phytosterol biosynthesis. 3. CYP87D18 catalyzed the oxidation of cucurbitadienol at C-11 to produce 11-oxo cucurbitadienol and 11-hydroxy cucurbitadienol. | |
| BCN3346 | Limocitrin |
| 1. Limocitrin is a constituent of citrus fruit peels, belongs to the family of Flavonols. | |
