Products with Anticoagulants bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN3721 | Ginsenoside Rk2 |
| Ginsenoside Rk1 has anti-tumor, and anti-platelet aggregation activities. Ginsenoside Rk1 can strongly inhibit permeability induced by VEGF, advance glycation end-product, thrombin, or histamine in human retinal endothelial cells, it reduces the vessel leakiness of retina in a diabetic mouse model; this anti-permeability activity of Rk1 is correlated with enhanced stability and positioning of tight junction proteins at the boundary between cells; Rk1 induces phosphorylation of myosin light chain and cortactin, which are critical regulators for the formation of the cortical actin ring structure and endothelial barrier. | |
| BCN3787 | Nothofagin |
| 1. Nothofagin has antioxidant activity. 2. Nothofagin and Aspalathin may have significant benefits in the treatment of diabetic complications. 3. Nothofagin and Aspalathin possess antithrombotic activity and offers a basis for development of a novel anticoagulant. 4. Nothofagin and Aspalathin possess anti-inflammatory activity by inhibiting hyperpermeability, expression of CAMs, and adhesion and migration of leukocytes, thereby endorsing its usefulness as a therapy for vascular inflammatory diseases. 5. Nothofagin and Aspalathin have potential to as an anti-sendothelial cell protein C receptor shedding reagent against phorbol-12-myristate 13-acetate and cecal ligation and puncture -mediated endothelial cell protein C receptor shedding. | |
| BCN3933 | Paeoniflorigenone |
| 1. Paeoniflorigenone is a depolarizing neuromuscular blocking agent, being similar to succinylcholine. 2. Paeoniflorigenone is cytotoxic and induces apoptosis selectively in the cancer cell lines. 3. Paeoniflorigenone may take part in improving blood circulation by inhibiting ether platelet aggregation and/or blood coagulation. 4. Paeoniflorigenone shows anti-inflammatory effects. | |
| BCN5009 | Morroniside |
| Morroniside has therapeutic effects on diabetic angiopathies, renal damage, lipid metabolism and inflammation and bone resorption. Morroniside can notably protect the brain from damage induced by focal cerebral ischemia which might be related to morroniside antioxidant and anti-apoptotic properties in the brain.Morroniside can decrease the level of cycloxygenase(Cox) and it may be the mechanism of morroniside on inhibiting the platelet aggregation induced by ADP in rabbits. | |
| BCN5187 | Heraclenin |
| 1. Heraclenin and imperatorin have an equally strong clastogenic effect . 2. Heraclenin can induce apoptosis in Jurkat leukemia cells. 3. Heraclenin has mutagenicity in Chlamydomonas reinhardii. 4. (+)-Heraclenin displays significant levels of antiplasmodial and moderate levels of antimicrobial activities. 5. Heraclenin has anticoagulant activity. 6. Heraclenin shows anti-inflammatory activity. | |
