Products with Antioxidants bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN5451 | Epitulipinolide diepoxide |
| 1. Epitulipinolide diepoxide has antioxidative and chemopreventive activities in skin melanoma cells, can significantly inhibit the proliferation of melanoma cells. 2. Epitulipinolide diepoxide possessea cytotoxic activity against KB cells. | |
| BCN5452 | Methyllinderone |
| 1. Methyllinderone has antioxidant property. 2. Methyllinderone is a human chymase inhibitor. 3. Methyllinderone shows moderate to weak antifungal activities against various pathogenic fungi. 4. Methyllinderone can inhibit farnesyl protein transferase with IC50 value of 55.3+/-4.1microM and selectively inhibit the growth of H-ras-transformed rat-2 cell lines with a GI50 value of 0.3 microM. 5. Methyllinderone shows significant cytotoxicity against mouse melanoma (B16-F10), human acetabulum fibrosarcoma (HT1080), and choronic myelogenous leukemia (K562) cancer cell lines with ED(50) values of 2.2, 2.5, 8.3 mug/ml, respectively. | |
| BCN5462 | Medioresinol |
| 1. Medioresinol possesses a lesishmanicidal activity and cardiovascular disease risk reduction. 2.(+)-Medioresinol has anti-bacterial, antifungal and anti-biofilm activities. 3. Medioresinol has antioxidative activity. 4. Medioresinol has antiamyloidogenic activity via reduction in the amount of β-secretase, it is a potentially valuable antiamyloidogenic agent for the prevention and treatment of Alzheimer disease. | |
| BCN5466 | Hirsutanonol |
| 1. Hirsutanonol or oregonin as an active ingredient composition for treating atopic dermatitis. 2. Hirsutanonol shows significant inhibitory effects on 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced cyclooxygenase-2 (COX-2) expression in immortalized human breast epithelial MCF10A cells. 3. Hirsutanonol has potent antioxidant activity, it shows significant free radical scavenging activity and exhibits inhibition effect on the mitochondrial lipid peroxidation. 4. Hirsutanonol shows potent cytotoxic activities against murine B16 melanoma cells and human SNU-C1 gastric cancer cells. 5. Hirsutanonol has chemoprotective effect on human lymphocytes DNA. 6. Hirustenone and hirsutanonol show promising anti-filarial activity both in vitro and in vivo studies. | |
| BCN5467 | Hirsutenone |
| 1. Hirsutenone exhibits anti-cancer effect against prostate cancer through a direct physical inhibition of Akt1/2. 2. Hirsutenone attenuates adipogenesis by directly targeting PI3K and ERK during MCE in 3T3-L1 preadipocytes, underscoring the potential therapeutic application of Hirsutenone in preventing obesity. 3. Hirsutenone may exert a preventive effect against microbial endotoxin lipopolysaccharide-induced inflammatory skin diseases through inhibition of ERK pathway-mediated NF-kappaB activation. 4. Hirsutenone has potent antioxidant activity, it shows significant free radical scavenging activity and exhibits inhibition effect on the mitochondrial lipid peroxidation. 5. Hirsutenone shows potent cytotoxic activities against murine B16 melanoma cells and human SNU-C1 gastric cancer cells. 6. Hirustenone and hirsutanonol show promising anti-filarial activity both in vitro and in vivo studies. | |
