Products with Antioxidants bioactivity

Cat.No. Product Name
BCN5475 Koaburaside
1. Koaburaside can suppress histamine release from mast cells, it may have anti-allergic inflammatory activity. 2. Koaburaside exhibits antioxidant activity with an IC50 value of 9.0μM, it shows weak inhibitory activity against influenza A neuraminidase.
BCN5479 Trilobatin
Trilobatin has anti-oxidant, and anti-inflammatory effects, it can increase superoxide dismutase (SOD) activity, and it potentially inhibits the lipopolysaccharide (LPS)-induced inflammatory response by suppressing the NF-κB signaling pathway. Trilobatin shows a strong inhibitory activity against α-glucosidase and a moderate inhibitory activity against α-amylase for management of postprandial hyperglycemia with less side effect.
BCN5480 Glabranin
1. Glabranine exerts a dose-dependent inhibitory effect in vitro on the dengue virus, it presents 70% inhibition on the dengue virus at a concentration of 25 microM. 2. Glabranin shows significant activities on DPPH free radical with the IC50 value of 240.20 ug/ml. 3. Glabranin or a derivative thereof could be used to stimulate hair growth. 4. Glabranin has antimicrobial activity.
BCN5487 Crategolic acid
Crategolic acid(Maslinic acid) has neuroprotective, anti-inflammatory, anti- osteoporosis, cytotoxic and antiviral activities, it suppresses RANKL-induced osteoclastogenesis through NF-κB and MAPK/AP-1 signaling pathways , and has beneficial effects on hypoxic neurons by suppressing iNOS activation.Crategolic acid as a feed additive to stimulate growth and hepatic protein-turnover rates in rainbow trout ( Onchorhynchus mykiss ).
BCN5504 Curcumin
Curcumin is a natural phenolic compound with diverse pharmacologic effects including antitumour, anti-bacteria, anti-fungicidal ,anti-edemic, hepatoprotective, anti-inflammatory, antioxidant, antiproliferative and antiangiogenic activities. Curcumin is an inhibitor of p300 histone acetylatransferase ((HATs)) and also shows inhibitory effects on NF-κB and MAPKs.Curcumin application causes markedly fast wound closure with well-formed granulation tissue dominated by fibroblast proliferation, collagen deposition, and complete early regenerated epithelial layer.

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