Products with Antioxidants bioactivity

Cat.No. Product Name
BCN4140 Vasicine
1. Vasicine is oxytocic and abortifacient agents. 2. Vasicine, a potential natural cholinesterase inhibitor, has been in development for treatment of Alzheimer's disease. 3. Vasicine can regulate the inflammatory reaction, have great potentials to develop safe medications for respiratory and reproductive medicine.
BCN4151 epsilon-Viniferin
1. Epsilon-viniferin shows a human cytochrome P450 enzymes inhition activity. 2. Epsilon-Viniferin is a bacteriostatic stilbenoid as it antagonized the bactericidal activity of vancomycin. 3. Epsilon-viniferin and epsilon-viniferin pentaacetate slightly reduce cell proliferation but might protect from cell degenerescence. 4. Epsilon-viniferin exhibits good antioxidant capacity in the DMSO/O(-)(2) polar system (IC50= 0.14 mM). 5. (-)-Trans-epsilon-viniferin is an inhibitor of noradrenaline and 5-hydroxytryptamine uptake and of monoamine oxidase activity, it may be of value as a structural template for the design and development of new antidepressant drugs.
BCN4152 alpha-Viniferin
Alpha-viniferin is a prostaglandin H2 synthase inhibitor, which has anti-inflammatory, anti-oxidant, anti-arthritis, and anti-tumor activities. Alpha-Viniferin inhibits AChE activity is specific, reversible and noncompetitive, in a dose-dependent manner, and the IC50 values of alpha-Viniferin were 2.0 microM. Alpha-Viniferin exhibits a dose-dependent inhibition on cyclooxygenase activity, where 50% of inhibition (IC50) was shown at a final concentration of about 7 microM, it down-regulates STAT-1-inducible inflammatory genes via inhibiting ERK-mediated STAT-1 activation in IFN-gamma-stimulated macrophages.
BCN4170 Hexacosyl (E)-ferulate
1. Hexacosyl (E)-ferulate displays significant antioxidant activity in the DPPH assay (RC50 = 0.0976 mg/mL). 2. Hexacosyl (E)-ferulate might be a chemotaxonomic marker in the genus Echinops.
BCN4171 Wogonin
Wogonin is an inhibitor of CDK9, which has anti-inflammatory and anti-tumor activities, it could be developed into an efficient natural sensitizer for resistant human myelogenous leukemia. It has a wide spectrum of targets including PGE2, NO, Nrf2, Src, MEK1/2, ERK1/2, NFκB,MLCK, MLC.

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