Products with Antiviral bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN5420 | Theaflavine-3,3'-digallate |
| 1. Theaflavin-3,3'-digallate is an inducer of oxidative stress and apoptosis. 2. A combination microbicide containing theaflavin-3,3'-digallate and lactic acid can reduce herpes simplex virus (HSV) transmission. 3. Theaflavin-3,3'-digallate may be useful chemoprevention agents for prostate cancer through suppressing the function of androgen and its receptor. 4. Theaflavin-3, 3'-digallate has strong antioxidant and antiangiogenic activities, it inhibits the tube formation of endothelial cells via decreased both MMP-2 and MMP-9 activities in vitro. 5. Theaflavin-3,3'-digallate may exert its anti-inflammatory and cancer chemopreventive actions by suppressing the activation of NFkappaB through inhibition of IkappaB kinase (IKK) activity. 6. Theaflavin-3,3'-digallate is a potent AMP-activated protein kinase (AMPK) activator with anti-adiposity activity in adipocytes, suggesting its potential application in functional foods and nutraceuticals for obesity management. 7. Theaflavin-3,3'-digallate can repress osteoclastogenesis and prevent wear debris-induced osteolysis via suppression of ERK pathway, it is a promising candidate for the treatment of osteoclast-related osteolytic diseases, such as wear debris-induced peri-implant osteolysis (PIO). | |
| BCN5456 | Yatein |
| 1. Yatein is a lignan precursor of podophyllotoxin, a key agent in anticancer drugs. 2. Yatein can significantly suppress HSV-1 multiplication in HeLa cells without apparent cytotoxicity. | |
| BCN5465 | Platyphyllonol |
| 1. Platyphyllonol-5-xylopyranoside is moderately active against KBNP-0028 (H9N2) avian influenza virus as compared with zanamivir. | |
| BCN5475 | Koaburaside |
| 1. Koaburaside can suppress histamine release from mast cells, it may have anti-allergic inflammatory activity. 2. Koaburaside exhibits antioxidant activity with an IC50 value of 9.0μM, it shows weak inhibitory activity against influenza A neuraminidase. | |
| BCN5480 | Glabranin |
| 1. Glabranine exerts a dose-dependent inhibitory effect in vitro on the dengue virus, it presents 70% inhibition on the dengue virus at a concentration of 25 microM. 2. Glabranin shows significant activities on DPPH free radical with the IC50 value of 240.20 ug/ml. 3. Glabranin or a derivative thereof could be used to stimulate hair growth. 4. Glabranin has antimicrobial activity. | |
