Products with Cardiovascular protection bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN4896 | Parthenolide |
| Parthenolide exhibits anti-cancer, anti-inflammatory, immunomodulatory, anti-Leishmania, and antimigraine effects, it inhibits nociception and neurogenic vasodilatation in the trigeminovascular system by targeting the TRPA1 channel.Parthenolide is also an inhibitor of the nuclear factor-kappaB pathway, can ameliorate cardiovascular derangement and outcome in endotoxic shock in rodents. | |
| BCN5004 | Ophiopogonin D |
| 1. Ophiopogonin D plays a protective role as an effective antioxidant in H2O2-induced endothelial injury, it can be therefore developed as a novel drug for the therapy of cardiovascular disorders. 2. Ophiopogonin D can attenuate doxorubicin-induced autophagic cell death by relieving mitochondrial damage in vitro and in vivo. 3. Ophiopogonin D and spicatoside A can increase mucin production and secretion, by directly acting on airway epithelial cells, they could be as expectorants in diverse inflammatory pulmonary diseases. 4. Ophiopogonin D inhibits MCF-7 cell growth via the induction of cell cycle arrest at the G2/M phase. | |
| BCN5042 | Benzyl cinnamate |
| Benzyl cinnamate, a flavouring agent isolated from various plant species, is used in heavy oriental perfumes and as a fixative. Benzyl cinnamate has anti-inflammatory activity, it can treat trachoma, corneal opacities, Meniere's syndrome and tinnitus aurum. | |
| BCN5346 | Protoveratrine A |
| 1. Protoveratrine A enhances the release of acetylcholine from the nerve terminals during the resting period and at low frequency of stimulation. 2. Protoveratrine A seems to involve at least in part an inhibition of dopaminergic neuron activity. 3. Protoveratrine A has depolarizing effects on the rat diaphram. 4. Protoveratrine A has some effects on cardiovascular and respiratory systems in rats in reducing the blood pressure and heart rate,prolonging the QTc interval,decreasing the respiratory rate and increasing the respiratory width. 5. Protoveratrine A can increase K + uptake from frog skeletal muscle and cause this tissue to release more calcium (Ca ++ ). 6. Protoveratrine A has anti-hypertensive action. | |
| BCN5376 | Salvianolic acid C |
| Salvianolic acid C has antioxidant effect, it exhibits potent XOD inhibitory activity with an IC(50) of 9.07 μM. Salvianolic acid C enhances the inhibitory effects on sEH might be efficient ways to improve its cardiovascular protective and anti-inflammatory effects. | |
