Benzyl cinnamate

CAS# 103-41-3

Benzyl cinnamate

Catalog No. BCN5042----Order now to get a substantial discount!

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Benzyl cinnamate: 5mg $17 In Stock
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Quality Control of Benzyl cinnamate

Number of papers citing our products

Chemical structure

Benzyl cinnamate

3D structure

Chemical Properties of Benzyl cinnamate

Cas No. 103-41-3 SDF Download SDF
PubChem ID 5273469 Appearance White solid
Formula C16H14O2 M.Wt 238.28
Type of Compound Phenylpropanoids Storage Desiccate at -20°C
Synonyms Benzyl 3-phenylpropenoate; Cinnamic acid benzyl ester; 3-Phenyl 2-propenoic acid benzyl ester
Solubility Soluble in ethanol and methanol; insoluble in water
Chemical Name benzyl (E)-3-phenylprop-2-enoate
SMILES C1=CC=C(C=C1)COC(=O)C=CC2=CC=CC=C2
Standard InChIKey NGHOLYJTSCBCGC-VAWYXSNFSA-N
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Benzyl cinnamate

The barks of Cinnamomum cassia Presl

Biological Activity of Benzyl cinnamate

DescriptionBenzyl cinnamate, a flavouring agent isolated from various plant species, is used in heavy oriental perfumes and as a fixative. Benzyl cinnamate has anti-inflammatory activity, it can treat trachoma, corneal opacities, Meniere's syndrome and tinnitus aurum.
TargetsImmunology & Inflammation related
In vivo

Benzyl cinnamate (Jacobson's solution) with vitamin A. A one-year experience in the treatment of cerebrovascular lesions.[Reference: WebLink]

Harlem Hospital Bulletin, 1960, 1:97-102.

Benzyl cinnamate (Jacobson's solution) with vitamin A. A one-year experience in the treatment of cerebrovascular lesions.

BENZYL CINNAMATE IN THE TREATMENT OF TRACHOMA AND CORNEAL OPACITIES.[Reference: WebLink]

Arch. Ophthalmol., 1936, 16(3):400-4.

In 1919 I introduced the use of Benzyl cinnamate in the treatment of tuberculosis. In order to inquire into the efficacy of this drug against tuberculosis, I used it first in the treatment of external forms of the disease, such as tuberculosis of the skin, mucous membranes and glands. These lesions being visible, it was easy to control and to follow the course of the disease. The results obtained proved worthy of interest and were confirmed by Darier and Jeanselme.1 My subsequent researches showed that the therapeutic action of the drug is not specific for tuberculosis.
CONCLUSIONS:
Its action can be seen wherever a focus of chronic inflammation is found, regardless of the nature of the agent which produces the lesion.It was by pure chance that Benzyl cinnamate found its application in the field of ophthalmology. While treating an Algerian Arab for glandular tuberculosis, I observed that while

Protocol of Benzyl cinnamate

Animal Research

Dibenzalacetone and benzyl cinnamate as non-steroidal anti-inflammatory compounds and compositions thereof[Reference: WebLink]

US4587260[P]. 1986.

A non-steroidal anti-inflammatory composition comprising an active anti-inflammatory agent having the formula: ##STR1## wherein R is ##STR2## The active agent is formulated with a pharmaceutically acceptable carrier for use in the treatment of pain, inflammation and other related symptoms on mammals. Benzyl cinnamate and dibenzalacetone are preferred.

Structure Identification
J Agric Food Chem. 2011 Jan 12;59(1):282-8.

Propolis specimens from different locations of central Italy: chemical profiling and gas chromatography-mass spectrometry (GC-MS) quantitative analysis of the allergenic esters benzyl cinnamate and benzyl salicylate.[Pubmed: 21126078]

Propolis is a beehive product popular in natural medicine thanks to its noteworthy properties. Propolis is non-toxic but is responsible for allergic reactions in sensitive individuals.
METHODS AND RESULTS:
In this paper, we propose a new gas chromatography-mass spectrometry (GC-MS) analytical methodology for the quantitative analysis of two allergenic esters in propolis specimens, benzyl salicylate and Benzyl cinnamate, and test it on specimens from different locations of central Italy. We also present the results obtained in the chemical characterization of the same specimens.
CONCLUSIONS:
The characterization showed that the resin fractions of all of the specimens are of poplar origin.

Benzyl cinnamate Dilution Calculator

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Benzyl cinnamate Molarity Calculator

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Preparing Stock Solutions of Benzyl cinnamate

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 4.1967 mL 20.9837 mL 41.9674 mL 83.9349 mL 104.9186 mL
5 mM 0.8393 mL 4.1967 mL 8.3935 mL 16.787 mL 20.9837 mL
10 mM 0.4197 mL 2.0984 mL 4.1967 mL 8.3935 mL 10.4919 mL
50 mM 0.0839 mL 0.4197 mL 0.8393 mL 1.6787 mL 2.0984 mL
100 mM 0.042 mL 0.2098 mL 0.4197 mL 0.8393 mL 1.0492 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Benzyl cinnamate

Fragrance material review on benzyl cinnamate.[Pubmed:18037214]

Food Chem Toxicol. 2007;45 Suppl 1:S40-8.

A toxicologic and dermatologic review of Benzyl cinnamate when used as a fragrance ingredient is presented.

Propolis specimens from different locations of central Italy: chemical profiling and gas chromatography-mass spectrometry (GC-MS) quantitative analysis of the allergenic esters benzyl cinnamate and benzyl salicylate.[Pubmed:21126078]

J Agric Food Chem. 2011 Jan 12;59(1):282-8.

Propolis is a beehive product popular in natural medicine thanks to its noteworthy properties. Propolis is non-toxic but is responsible for allergic reactions in sensitive individuals. In this paper, we propose a new gas chromatography-mass spectrometry (GC-MS) analytical methodology for the quantitative analysis of two allergenic esters in propolis specimens, benzyl salicylate and Benzyl cinnamate, and test it on specimens from different locations of central Italy. We also present the results obtained in the chemical characterization of the same specimens. The characterization showed that the resin fractions of all of the specimens are of poplar origin.

Description

Benzyl cinnamate, occurs in Balsam of Peru and Tolu balsam, in Sumatra and Penang benzoin, and as the main constituent of copaiba balsam, is used in heavy oriental perfumes and as a fixative.

Keywords:

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