Products with Genotoxicity bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN3837 | alpha-Asarone |
| 1. Alpha-Asarone shows insecticidal activity. | |
| BCN4074 | Methyleugenol |
| Methyleugenol (ME) is a natural constituent of the essential oils of a number of plants widely used in foodstuffs as flavouring agents, in view of the carcinogenic potential of ME, the need to check its presence in food products with effective analytical methods. ME has elaxant and antispasmodic actions on guinea-pig isolated ileum, it also has antinociceptive, anti-inflammatory, and insecticidal properties.ME can inhibit the production of nitric oxide and decreased the protein expression of inducible nitric oxide synthase, it down-regulates the production of pro-inflammatory cytokines in the ischemic brain as well as in immunostimulated mixed glial cells. | |
| BCN5625 | Verminoside |
| 1. Verminoside exhibits anti-inflammatory, anti-bacterial and anti-properties. 2. Verminoside induces genotoxicity on human lymphocytes, involved with PARP-1 and p53 proteins. 3. Verminoside shows significant anti-inflammatory effects, can inhibit both iNOS expression and NO release in the LPS-induced J774.A1 macrophage cell line. 4. Verminoside attenuates intracellular ROS and stress (oxidative and thermal) level promoting longevity, the longevity and stress modulation can be attributed to VMS-mediated alterations in daf-16 expression which regulates insulin signaling pathway. | |
| BCN5681 | Tryptophol |
| Tryptophol is an aromatic alcohol found as a secondary product of alcoholic fermentation that induces sleep in humans. Tryptophol can inhibit the infection/replication of GVE2 by interacting with the host's Clp protease. Tryptophol can inhibit the proliferation of U937 cells by inducing apoptosis via a pathway involving caspase-8 followed by caspase-3. Tryptophol induces apoptosis through Death Receptor (DR) 5 and that the resistance of peripheral blood lymphocytes (PBL) to tryptophol-induced apoptosis might be due to competition from decoy receptor (DcR). | |
| BCN5698 | 2,6-Dimethoxy-1,4-benzoquinone |
| 2,6-Dimethoxy-1,4-benzoquinone exhibits strong antibacterial activities against S. pyogenes, S. mitis, and S. mutans with MIC values of 7.8, 7.8, and 15.6 ug/mL, and MBC values of 7.8, 7.8, and 31.2 ug/mL, respectively. 2,6-Dimethoxy-1,4-benzoquinone can produce genotoxic effects in patients taking dimethophrine. | |
