Products with Genotoxicity bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN2332 | Forskolin |
| Forskolin is a ubiquitous activator of eukaryotic adenylyl cyclase (AC) in a wide variety of cell types, commonly used to raise levels of cAMP in the study and research of cell physiology. Forskolin has antitumor, antioxidant and antiinflammatory actions, it may cause genotoxic effects. Chronic administration of Forskolin can decrease fasting blood glucose levels, it is effective in preventing diet induced obesity. | |
| BCN2538 | Olaquindox |
| Olaquindox, as one of the antimicrobial growth accelerants, is usually used in livestock production to improve feed efficiency. Olaquindox induces apoptosis of HepG2 cells through a caspase-9 dependent mitochondrial pathway, might be suppressed through p38 MAPK and ROS-JNK pathways; it induces autophagy in HepG2 cells is upregulated by Beclin 1 but downregulated by ROS-dependent JNK.Olaquindox has genotoxic activity. | |
| BCN2818 | Elemicin |
| Elemicin has anticancer, and antifungal activities, it exhibits anticholinergic-like effects in humans. | |
| BCN3386 | 5,7-Di-O-methylquercetin |
| 1. 5,7-Di-O-methylquercetin is a genotoxic compound from S. skinneri. | |
| BCN3762 | Coronaridine |
| 1. Coronaridine is an antitumor agent. 2. Coronaridine congeners inhibit hα3β4 AChRs by blocking the ion channel's lumen and probably by additional negative allosteric mechanisms by interacting with a series of non-luminal sites. | |
