Products with Hepatoprotective bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN5464 | Skullcapflavone I |
| 1. Skullcapflavone I selectively induces apoptosis in T-HSC/Cl-6 cells via caspase-3 and caspase-9 activation. 2. Skullcapflavone I has anti-inflammatory and anti-allergic potential, it can significantly inhibit LPS stimulated NO and PGE(2) release in J774A.1 macrophages and inhibit LPS induced IL-6 production in a concentration dependent manner. | |
| BCN5477 | Acuminatin |
| 1. (+)-trans-Acuminatin, and (+)-cis-acuminatin show weak activity against platelet aggregation with IC50 values of 108.5 and 90.02 uM, respectively. 2. (-)-Acuminatin, and machilin G show dose-dependent potent inhibitory activities against PLCgamma1 in vitro with IC50 values ranging from 8.8 to 26.0 microM, the inhibition of PLCgamma1 may be an important mechanism for an antiproliferative effect on the human cancer cells, therefore, these inhibitors may be utilized as cancer chemotherapeutic and chemopreventive agents. 3. (-)-Acuminatin exerts hepatoprotective activities, perhaps by serving as a potent antioxidant. | |
| BCN5500 | Betulonic acid |
| Betulonic acid has anti-cancer , anti-HIV,hepatoprotective and anti-inflammatory activities, it has antiviral activity against herpes simplex virus, it also suppresses ECHO 6 virus reproduction. Betulonic acid derivatives have a promising cytostatic activity in vitro and could be used as potential leads for the development of new type of anti-cancer agents. | |
| BCN5508 | Arjunolic acid |
| Arjunolic acid has antioxidant, anti-inflammatory, antinociceptive and anticholinesterasic (AChE and BuChE) activities, it may as promising targets for the development of innovative multi-functional medicines for Alzheimer desease treatment.Arjunolic acid protects cardiac tissues from both extrinsic and intrinsic cell death pathways.Arjunolic acid exhibits better protection against histamine release than against acetylcholine release, anti-asthmatic and anaphylactic activity of it may be possibly due to membrane stabilizing potential and inhibition of antigen induced histamine and acetylcholine release. Arjunolic acid protects cardiac tissues from both extrinsic and intrinsic cell death pathways, it also has antitumor activity. | |
| BCN5522 | alpha-Boswellic acid |
| alpha-Boswellic acid (α-BA)has gastroprotective properties by decreasing oxidative stress and the Nrf2/HO-1 pathway. α-BA also has protective effects against acetaminophen (APAP)-induced hepatotoxicity in Balb/ cA mice.α-BA could be considered as a potent therapeutic agent for prevention and decreasing the progression of Alzheimer’s hallmarks, it can efficiently reduce hyperphosphorylated Tau (Ser404) in STZ-treated astrocytes and decrease ROS generation and promote proliferation of astrocytes through elevating Survivin expression. | |
