Products with Immunomodulators Bioactivity

Explore BioCrick products associated with Immunomodulators biological activity, including catalog numbers, product names and available bioactivity information.

Cat. No.	Product Name
BCN2363	Turkesterone
1. Turkesterone is a phytoecdysteroid possessing an 11alpha-hydroxyl group, also is an analogue of the insect steroid hormone 20-hydroxyecdysone. 2. Turkesterone has immunomodulating and antistress activity, can increase the adaptation capacity of mice under immobilization-induced stress conditions.
BCN2385	Indirubin
Indirubin is a potent cyclin-dependent kinases and GSK-3β inhibitor with IC50 of about 5 μM and 0.6 μM. Indirubin has anticancer, anti-inflammatory,antiviral,anti-allergic contact dermatitis effects. Each indirubin derivative acts on the DNA binding of NF-Y and represses the MDR1 gene promoter with tumor cell-type specificity.Indirubin derivatives have a potential to be used as an adjunct to antiviral therapy for the treatment of severe human H5N1 disease.
BCN2395	Sclareol
Sclareol possesses anti-cancer, anti-osteoarthritic, immune-regulation and anti-inflammatory activities, it inhibits the MMPs, iNOS and COX-2 expression on mRNA and protein levels, while increases the TIMP-1 expression, and over-production of NO and PGE2 is also suppressed by Sclareol ameliorated cartilage degradation. Sclareol induces plant resistance to root-knot nematode partially through ethylene-dependent enhancement of lignin accumulation.
BCN2532	Mogroside IV
Mogrosides IV is a sweet minor cucurbitane glycoside, it exhibits maltase inhibitory effect. Mogroside IV, Mogroside V and combinations thereof act as a Toll -Like Receptor -4 agonist and immune stimulant that can be utilized for both therapeutic vaccine design in cancer and for other pathogenic agents; therapy with Mogroside IV, Mogroside V and combinations thereof are also presented to created immune clearance of a viral infection.
BCN2549	Dehydrocavidine
1. Dehydrocorydaline has antitumor activity. 2. Dehydrocorydaline inhibits MCF-7 cell proliferation by inducing apoptosis mediated by regulating Bax/Bcl-2, activating caspases as well as cleaving PARP. 3. Dehydrocorydaline reduces the viability of macrophage-derived RAW264.7 cells and primary macrophages in the presence of LPS. 4. Dehydrocorydaline inhibits the elevation of mitochondrial membrane potential and induces ATP depletion in LPS-stimulated macrophages but neither affects basal mitochondrial membrane potential nor ATP content in non-stimulated macrophages.

Immunomodulators Bioactivity Products