Products with
Immunomodulators bioactivity
Cat.No.
|
Product Name
|
BCN2560 |
Cirsilineol
|
1. Cirsilineol might be potentially useful for treating T-cell-mediated human inflammatory bowel diseases.
2. Cirsilineol has anti-proliferative activity against cancer cells by the induction of apoptosis via the mitochondrial pathway. |
BCN2586 |
Plumbagin
|
Plumbagin, a potential natural FOXM1 inhibitor, has anticancer, and anti-fibrotic activies, it inactivates the NF-κB/TLR-4 pathway that is associated with inflammatory reactions, thereby mitigating liver fibrosis. Plumbagin offers significant protective role against DEX-induced cellular damage via regulating oxidative stress, apoptosis, and osteogenic markers. |
BCN2650 |
Oxoglaucine
|
Oxoglaucine exerts immunomodulatory effect in vivo in a dose-dependent and protocol-dependent manner, it also exhibits significant antiplatelet aggregation activity against rabbit platelets induced by thrombin, arachidonic acid, collagen or platelet activating factor.
Oxoglaucine and pachypodol are anti-picornavirus compounds, phosphatidylinositol 4-kinase III beta (PI4KB) as the direct target of them. |
BCN2655 |
Periplocin
|
Periplocin has anti-cancer, and potent immunoregulatory effects, it induces apoptosis and inhibits growth of cancer cells by the beta-catenin/Tcf signaling pathway. Periplocin is used for treatment of rheumatoid arthritis, reinforcement of bones and tendons, palpitations or shortness of breath and lower extremity edema in traditional medicine. |
BCN2663 |
Demethylwedelolactone
|
Demethylwedelolactone has trypsin inhibitory effect, it exerts anti-invasive growth effect on breast cancer cells. |