Products with Immunomodulators bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN3231 | Ponicidin |
| 1. Ponicidin has immunoregulatory and anti-inflammatory functions . 2. Ponicidin has anti-viral function especially in the upper respiratory tract infection. 3. Ponicidin has anti-leukemia activity, by inducing apoptosis, downregulation of survivin as well as Bcl-2 expressions. 4. Ponicidin has anti-cancer activity against gastric carcinoma and lung cancer; can inhibit growth and induce apoptosis of gastric carcinoma cell line MKN28, via the signaling pathway regulated by Janus kinase 2 (JAK2) and signal transducers and activators of transcription 3 (STAT3). | |
| BCN3338 | 1-Dehydro-10-gingerdione |
| 1. 1-Dehydro-10-gingerdione has anti-inflammatory action, the molecular target is Myeloid differentiation protein. 2. 1-Dehydro-10-gingerdione involves in the suppression of NF-κB-regulated gene expression in LPS-activated macrophages, has therapeutic potential in NF-κB-associated inflammation and autoimmune disorders. | |
| BCN3432 | Chikusetsusaponin IVa |
| Chikusetsusaponin IVa is a novel AMPK activator, can induce insulin secretion from βTC3 cells via GPR40 mediated calcium and PKC pathways, may be developed into a new potential for therapeutic agent used in T2DM patients.Chikusetsusaponin IVa exerts antithrombotic effects, including minor hemorrhagic events. | |
| BCN3468 | Skimmianin |
| 1. Skimmianine is a new inhibitor against the Leishmania APRT enzyme. 2. Skimmianine has a selective inhibitory effect on the 5-hydroxytryptamine-induced vasopressor responses of rats. 3, Skimmianine is a strong acetylcholinesterase (AChE) inhibitor. 4. Skimmianine has anti-inflammatory properties. 5. Skimmianine has leishmanicidal effect , it is thus a promising drug candidate for L. braziliensis due to its potent immunomodulatory activity. | |
| BCN3536 | 3-Hydroxy-1,5-diphenyl-1-pentanone |
| 1. (+)-3-Hydroxy-1,5-diphenyl-1-pentanone exhibits both immunomodulatory and anti-tumor activity. | |
