Products with Nephroprotective bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN1183 | Ergosta-4,6,8(14),22-tetraen-3-one |
| 1. Ergosta-4,6,8(14),22-tetraen-3-one can induce G2/M cell cycle arrest and apoptosis in human hepatocellular carcinoma HepG2 cells, these results would be useful for the further utilization of many medicinal fungi in cancer treatment. 2. Ergosta-4,6,8(14),22-tetraen-3-one has cytotoxic activity against human gastric cancer cell. 3. Ergosta-4,6,8(14),22-tetraen-3-one treatment can confer protection against early renal injury in a rat model of aristolochic acid (AA) nephropathy, early administration of it may prevent the progression of renal injury and the subsequent renal fibrosis in AA nephropathy. 4. Ergosta-4,6,8(14),22-tetraen-3-one has inhibitory activity of nitric oxide production in RAW 264.7 cells stimulated by lipopolysaccharide was examined and shows a potential activity with the IC(50) value of 28.96 microM. | |
| BCN1223 | Nuciferine |
| Nuciferine possesses anti-diabetic, anti-obesity, anti-hyperlipidemia, anti-hypotensive, anti-arrhythmic, vasorelaxant, and insulin secretagogue activities. Nuciferine may be potential for the prevention and treatment of hyperuricemia with kidney inflammation. It inhibited tumor-promoting effect of nicotine involving Wnt/β-catenin signaling in non-small cell lung cancer. | |
| BCN2225 | Thiamine hydrochloride |
| Thiamine hydrochloride is an efficient catalyst for the synthesis of amidoalkyl naphthols, it has prophylactic potential on lead induced lipid peroxidation in rat liver and kidney. Thiamine hydrochloride complex as a new anti-diabetic candidate. | |
| BCN2386 | Tangeretin |
| Tangeretin is a Notch-1 inhibitor, has antiproliferative, antiinvasive, antimetastatic and antioxidant activities.Tangeretin has therapeutic potential for melanoma and melanoma-associated depigmentation, because it can induce hyperpigmentation through the activation of melanogenic signaling proteins and initiation of sustained ERK2 expression. | |
| BCN2389 | Silychristin |
| Silychristin is a plant growth regulator, is an anti-hepatotoxic agent, is also an inhibitor of horseradish peroxidases and lipoxygenase. | |
