Products with Neuroprotection bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN1279 | (-)-Bilobalide |
| Bilobalide possesses anticonvulsant, insecticidal, and cardioprotective effects. Bilobalide exerts protective and trophic effects on neurons, the PI3K/Akt pathway may be involved in the protective effects of bilobalide; it also can protect PC12 cells from A beta 25-35-induced cytotoxicity, it dose-dependently attenuates the cytotoxic effect of A beta 25-35. | |
| BCN1289 | Sesamolin |
| Sesaminol possesses antioxidative activity, can inhibit lipid peroxidation in rat liver and kidney. It also shows neuroprotection effect on hypoxic neuronal and PC12 cells through the suppression of ROS generation and MAPK activation. | |
| BCN1312 | Chondroitin sulfate |
| Chondroitin sulfate has anti-inflammatory and chondroprotective actions ,it has been widely used in the treatment of osteoarthritis. Chondroitin sulfate reduces inflammation mediators and the apoptotic process and is able to reduce protein production of inflammatory cytokines, iNOS and MMPs.Chondroitin sulfate is a regulator of neuronal patterning in the retina, in the developing mammalian retina, gradual regression of chondroitin sulfate may help control the onset of ganglion cell differentiation and initial direction of their axons. | |
| BCN1318 | 3,5,9-Trihydroxyergosta-7,22-dien-6-one |
| 1. 3β,5α,9α-Trihydroxy-ergosta-7,22-dien-6-one in the presence of NGF (20 ng/mL) exerts a significant increase in neurite-bearing cells. | |
| BCN1441 | 14-Deoxy-11,12-didehydroandrographolide |
| 14-Deoxy-11,12-didehydroandrographolide has hypotensive, anti-inflammatory, anti-asthma, and anti-cancer actions, it causes negative chronotropic action and antagonised isoproterenol-induced positive chronotropic actions in a non-competitive and dose-dependent manner. 14-Deoxy-11,12-didehydroandrographolide can effectively ameliorate astrocytic pro-inflammatory reactions and prevent PC12 cell death with different efficacies, it may be candidates for treatment of spinal-cord injury and neurodegeneration. | |
