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Natural Products from Atractylodes lancea

Natural Products Isolated from Atractylodes lancea

BioCrick provides high-purity natural products and bioactive compounds isolated and purified from natural sources for scientific research.

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  • Broad structural diversity and coverage of biological activities.
  • Product activity information can be supported by published literature, patents and research reports.
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Natural products isolated from Atractylodes lancea
Natural products isolated from Atractylodes lancea

Natural Products from Atractylodes lancea

10 natural product s associated with Atractylodes lancea

Natural products and bioactive compounds from Atractylodes lancea
Catalog No. Product Name CAS Number COA
BCN5796 Adenosine
Adenosine chemical structure
58-61-7 COA
BCN1044 Atractylenolide II
Atractylenolide II chemical structure
73069-14-4 COA
BCN1045 Atractylenolide III
Atractylenolide III chemical structure
73030-71-4 COA
BCN6292 Atractylodin
Atractylodin chemical structure
55290-63-6 COA
BCN5383 Atractyloside A
Atractyloside A chemical structure
126054-77-1 COA
BCN6294 beta-Eudesmol
beta-Eudesmol chemical structure
473-15-4 COA
BCN5581 Osthol
Osthol chemical structure
484-12-8 COA
BCN5958 Puerarin
Puerarin chemical structure
3681-99-0 COA
BCN6059 Syringin
Syringin chemical structure
118-34-3 COA
BCN4090 Uridine
Uridine chemical structure
58-96-8 COA

References

Endophytic Pseudomonas induces metabolic flux changes that enhance medicinal sesquiterpenoid accumulation in Atractylodes lancea.[Pubmed: 30081324]


The bacterial endophyte Pseudomonas fluorescens ALEB7B significantly enhances photosynthate accumulations in Atractylodes lancea. These carbohydrates are preferentially used by the host plant to synthesize secondary metabolites, rather than to increase plant biomass accumulation. Mechanisms underlying the allocation of endophyte-increased carbohydrate in different plant metabolic processes are largely unknown. We have studied how P. fluorescens ALEB7B enhances photosynthate accumulation and how bacterial elicitors regulate metabolic flux and increase medicinal sesquiterpenoid formation in A. lancea using the sterile tissue culture plantlets. P. fluorescens ALEB7B enhances plant photosynthate accumulation by synthesizing and secreting indole-3-acetic acid, which has been demonstrated using high-performance liquid chromatography analysis. The increased endogenous indole-3-acetic acid promotes plant root development and then assimilation. Increased carbohydrates provide the material basis for the formations of terpenoid hydrocarbon scaffolds, which has been proved using gas chromatography analysis. Further, protein and polysaccharide elicitors secreted by P. fluorescens ALEB7B have been separated and purified from the bacterial fermentation broth, which have been applied to A. lancea plantlets. Both elicitors can stimulate the conversions of terpenoid hydrocarbon scaffolds to oxygenous sesquiterpenoids, the active medicinal ingredients in A. lancea, by triggering the oxidative burst in planta. Moreover, this study separates an ABC transporter substrate-binding protein from protein elicitors secreted by P. fluorescens ALEB7B with an ÄKTA Prime Plus Purifier System and firstly shows that this protein is essential to induce oxygenous sesquiterpenoid accumulation in A. lancea. This study provides new perspectives for mechanisms of medicinal oxygenous terpenoid synthesis, which has important reference values to the cultivation of medicinal plants that have terpenoids as their active ingredients, such as Artemisia annua and Taxus chinensis.


Two new thiophene polyacetylene glycosides from Atractylodes lancea.[Pubmed: 29614875]


Phytochemical investigation on the rhizomes of Atractylodes lancea led to the isolation of two new thiophene polyacetylene glycosides (1 and 2) and six known compounds (3-8). Their structures were elucidated based on the extensive spectroscopic data (UV, IR, 1D and 2D NMR, and HRESIMS). The absolute configurations of new compounds were established by calculated and experimental circular dichroism. All the compounds were assessed on the lipopolysaccharide-induced NO production in BV2 cells and compounds 3, 7, and 8 showed moderate inhibitory activities.