Hot Products
Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.
Hot products from the professional high-purity natural products manufacturer
| Cat.No. | Product Name |
|---|---|
| BCN8856 | Rhaponticin 6''-O-gallate |
| Rhaponticin 6''-O-gallate showed inhibitory activity of NO production in lipopolysaccharide-activated macrophages, (IC50 = 11-69 microM). | |
| BCN8857 | Hellebrigenin |
| Hellebrigenin has anti-hepatoma activities, it induces cell cycle arrest and apoptosis in human hepatocellular carcinoma HepG2 cells through inhibition of Akt. Hellebrigenin exhibites moderate to strong activity against human HL-60, SF-295, MDA-MB-435, and HCT-8 cancer cell strains without hemolysis of mouse erythrocytes. | |
| BCN8859 | 3beta-Methoxy-2,3-dihydrowithaferin A |
| 3beta-Methoxy-2,3-dihydrowithaferin A has cytoprotective activity, it protects normal cells against stress. | |
| BCN8863 | 7-Methylcoumarin |
| 7-Methylcoumarin is an inhibitor for CYP2A6. It has strong hepatoprotective activity, which could be attributed to its potent antioxidant effects. | |
| BCN8864 | Isorhamnetin 7-O-glucoside |
| Isorhamnetin 7-O-glucoside has antioxidant activity, it showed the peroxynitrite and DPPH scavenging activities with IC50 values of 2.07 /- 0.17 and 13.3 microM, respectively. | |
| BCN8865 | 5,7,3',4',5'-Pentamethoxyflavone |
| 3',4',5',5,7-Pentamethoxyflavone has anti-inflammatory and cancer chemopreventive activities. 3',4',5',5,7-Pentamethoxyflavone could be used as an effective adjuvant sensitizer to increase the efficacy of chemotherapeutic drugs by downregulating Nrf2 signaling pathway, it sensitizes Cisplatin-resistant A549 cells to Cisplatin by inhibition of Nrf2 pathway. | |
| BCN8866 | 7-Ethoxyrosmanol |
| 7-Ethoxyrosmanol has cytotoxic and antimicrobial activities. | |
| BCN8867 | Piperlonguminine |
| Piperlonguminine is an efficient depigmenting agent with a novel mechanism of action. It has potent antitumor, antitrypanosomal, anti-hyperlipidemic, anti-platelet and anti-melanogenesis activities. Piperlonguminine obviously improves hepatocyte fatty degeneration of alcoholic fatty liver in mice, it can effectively prevent the occurrence and development of alcoholic fatty liver. | |
