Hot Products

Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.

Hot products from the professional high-purity natural products manufacturer

Cat.No. Product Name
BCN8870 N-(p-Coumaroyl) serotonin
N-(p-Coumaroyl) serotonin has antioxidant, cardioprotective effects after ischemia and antitumor activity, it may be beneficial in improving vascular distensibility and in reducing cardiovascular risk.N-(p-Coumaroyl) serotonin has a suppressive effect on proinflammatory cytokine production from monocytes, and this effect is based in part on the suppression of cytokine mRNA expression through inhibition of NF-kappaB activation.
BCN8872 Hydroxy-alpha-sanshool
Hydroxy-alpha-sanshool exerts antiobesity and hypolipidemic activities in HFD rats by reducing liver oxidative stress and thus could be considered as a potential candidate drug to cure or prevent obesity and hyperlipidemia. It also has analgesic properties, it activates TRPV1 and TRPA1 in sensory neurons.
BCN8873 Aegeline
Aegeline has anti-diabetic and anti-dyslipidemic activities, it inspired synthesis of novel amino alcohol and thiazolidinedione hybrids with antiadipogenic activity in 3T3-L1 cells, it also inspired synthesis of novel β3-AR agonist improves insulin sensitivity in vitro and in vivo models of insulin resistance. Aegeline mimics the yeast SNARE protein Sec22p in suppressing α-synuclein and Bax toxicity in yeast.
BCN8874 Caulophyllogenin
Caulophyllogenin in the inhibition of pro-inflammatory cytokine secretion, including IL-12 p40, IL-6, and TNF-α, and for prevention and treatment of inflammatory diseases.
BCN8804 Silyamandin
Silyamandin may have antihepatotoxic and chemopreventive activities.
BCN8805 (+)-δ-Tocopherol
(+)-Delta-Tocopherol has antioxidant activity.
BCN8820 Quercetin 3-O-rutinoside-1-2-O-rhamnoside
Quercetin 3-O-rutinoside-(1→2)-O-rhamnoside shows α-glucosidase inhibitory activity, it has anti-diabetic potential.
BCN8849 Hydroxy-γ-sanshool
Hydroxy-γ-sanshool is a pungent compound, it can cause oral numbness.