Hot Products
Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.
Hot products from the professional high-purity natural products manufacturer
| Cat.No. | Product Name |
|---|---|
| BCN8704 | Xanthoangelol B |
| Xanthoangelol B and its derivative PM-56 were shown to bind directly to SaeS and inhibit its histidine kinase activity, which suggests a possibility of a broad spectrum inhibitor of histidine kinases. Xanthoangelol B inhibited the phenylephrine-induced vasoconstriction most strongly, and the inhibitory mechanism of it on phenylephrine-induced vasoconstriction might involve the direct inhibition of smooth muscle functions through the reduction of [Ca2+]i elevation without affecting EDRF/NO production. | |
| BCN8703 | Isololiolide |
| Isololiolide has phytotoxicity, it inhibited seedling growth of cress and barnyard grass. It also showed in vitro activity against both trypomastigote and intracellular amastigotes of Trypanosoma cruzi, with IC50 values of 32 µM and 40 µM, respectively. Isololiolide is an antioxidant response element (ARE) inducer, it has anti-inflammatory activity. It can exert a selective cytotoxic activity on hepatocarcinoma HepG2 cells as well as induce apoptosis through the modulation of apoptosis-related proteins. | |
| BCN8707 | Pilosidine |
| Pilosidine has vasoconstrictor activity, it showed facilitating effect on adrenaline evoked contractions in rabbit aorta isolated preparations. | |
| BCN8708 | Isocarlinoside |
| Isocarlinoside, L-malic acid, trans-aconitic acid, (+)-isocitric acid , 5-O-caffeoylquinic acid, 4-O-caffeoylquinic acid, 2"-O-rhamnosylisoorientin, and 7-O-(2"-O-glucuronosyl)glucuronosyltricin showed high antifeeding activity against brown planthopper only when they were combined. | |
| BCN8709 | Asiaticoside B |
| Asiaticoside B has notable cytotoxicity against HepG2 and MCF-7 cancer cell lines. | |
| BCN8712 | Methyl caffeate acid |
| Methyl caffeate acid shows anti-complementary activity. | |
| BCN8718 | Nagarine |
| Nagarine has toxic and analgesic effects. | |
| BCN8716 | Indole-3-acetic acid |
| Indole-3-acetic acid , a well-known phytohormone, can also be a signaling molecule in bacteria and therefore can have a direct effect on bacterial physiology. | |
