Hot Products
Hot products from BioCrick which is a professional high-purity natural products manufacturer are well known to scientists around the world because of their high purity and stability. Each product is a chemical compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life.Natural products remain the best sources of drugs and drug leads, and this remains true today despite the fact that many pharmaceutical companies have deemphasized natural products research in favor of HTP screening of combinatorial libraries during the past 2 decades. From 1940s to date, 131 (74.8%) out of 175 small molecule anticancer drugs are natural product-based/inspired, with 85 (48.6%) being either natural products or derived therefrom. From 1981 to date, 79 (80%) out of 99 small molecule anticancer drugs are natural product-based/inspired, with 53 (53%) being either natural products or derived therefrom. Among the 20 approved small molecule New Chemical Entities (NCEs) in 2010, a half of them are natural products.
Hot products from the professional high-purity natural products manufacturer
| Cat.No. | Product Name |
|---|---|
| BCN8813 | Rhaponticin 2''-O-gallate |
| Rhaponticin 2''-O-gallate showed inhibitory activity of NO production in lipopolysaccharide-activated macrophages, (IC50 = 11-69 microM). | |
| BCN8814 | 2,4,7-Trihydroxy-9,10-dihydrophenanthrene |
| 2,4,7-Trihydroxy-9,10-dihydrophenanthrene showS the DPPH free radical scavenging activity with EC(50) from 8.8 to 55.9 microM. | |
| BCN8817 | 2-Hydroxy-1-Methoxyaporphine |
| 2-Hydroxy-1-Methoxyaporphine can inhibit CYP2D6 activity, it also increase the glucose consumption significantly as rosiglitazone. | |
| BCN8821 | 5,7,3',4'-Tetramethoxyflavone |
| 5,7,3',4'-Tetramethoxyflavone (TMF) possesses various bioactivities, including antifungal, antimalarial, antimycobacterial, and anti-inflammatory activities; it also exhibits chondroprotective activity by targeting β-catenin signaling in vivo and in vitro. TMF protects chondrocytes from ER stress-induced apoptosis through regulation of the IRE1α pathway.TMF inhibits the expression of tyrosinase, tyrosine-related protein (TRP)-1, and TRP-2 mRNA, which could be the mechanism of its melanogenesis inhibitory activity. | |
| BCN8822 | Combretol |
| Combretol has leishmanicidal activity, it showed moderate activity (growth inhibition 87.3 and 73.0 %, respectively, at 50 µM) against a multidrug-resistant L. tropica line. Combretol also shows weakly active cytotoxic activity. | |
| BCN8823 | Ardisiacrispin B |
| Ardisiacrispin B displays cytotoxic effects in multi-factorial drug resistant cancer cells via ferroptotic and apoptotic cell death. | |
| BCN8828 | Isorhamnetin 3,7-O-diglucoside |
| Isorhamnetin 3,7-O-diglucoside may have antioxidant activity. | |
| BCN8832 | Randialic acid B |
| Randialic acid B shows significant cell-protective effects against H2O2-induced H9c2 cardiomyocyte injury. | |
